Tu Fulai, Yang Ruizhe, Wang Weixiang, Li Rui, Du Guoping, Liu Yangyang, Li Wei, Wei Pingmin
Key Laboratory of Environmental Medicine Engineering, Department of Epidemiology and Health Statistics, School of Public Health, Southeast University, Nanjing, 210009, People's Republic of China.
Department of Prevention and Health Care, Children's Hospital of Nanjing Medical University, Nanjing, 210008, People's Republic of China.
Infect Drug Resist. 2022 Jun 15;15:3063-3073. doi: 10.2147/IDR.S365728. eCollection 2022.
We aimed to describe the knowledge, attitude and practice (KAP) status of hepatitis B virus (HBV) among freshmen who were in the class of 2020 and from Jiangsu Province.
A random multistage sampling had been used to screen freshmen to conduct online questionnaire. The chi-square test was applied for pairwise comparison between sub-groups. Lasso regression and logistic regression were used to analyze the influencing factors of KAP about HBV. A structural equation model was established to explore the relationships among KAP of HBV.
The total awareness rate of HBV among freshmen was 63.1%. More than 50% of freshmen reported that they were not willing to live with hepatitis B carriers. Only 51.0% of students had been immunized against HBV. The knowledge of HBV among students whose fathers had college/bachelor degree or above was 1.464 times higher than those whose fathers' education level was junior high school or below (95% CI = 1.2771.677). Both of positive attitude and behavior among female students were 1.424 times (95% CI = 1.3291.525) and 1.468 times (95% CI = 1.2911.669) than that within male students, respectively. The positive behaviors of students whose mothers had college education or above were 1.347 times higher than those whose mothers had the degree of junior high or below (95% CI = 1.1471.582). Students who living with their parents were 1.167 times likely to have positive behaviors than those who living in other methods (95% CI = 1.020~1.334). The structural equation model had shown that the direct effect of knowledge on preventive motivation, attitude and behavior was 0.28, 0.53 and 0.10, respectively.
The population of freshmen still was far from a comprehensive understanding of HBV prevention and treatment. It is suggested that administrators of colleges and universities should pay more attentions to education of HBV knowledge as well as take multi-channel measures for prevention and management.
本研究旨在描述2020级江苏省大一新生对乙型肝炎病毒（HBV）的知识、态度和行为（KAP）状况。
采用随机多阶段抽样方法对大一新生进行筛选，以开展在线问卷调查。采用卡方检验对亚组间进行两两比较。运用套索回归和逻辑回归分析HBV-KAP的影响因素。建立结构方程模型以探究HBV-KAP之间的关系。
大一新生对HBV的总体知晓率为63.1%。超过50%的大一新生表示不愿意与乙肝携带者同住。仅有51.0%的学生接种过乙肝疫苗。父亲拥有大专及以上学历的学生对HBV的知晓率比父亲学历为初中及以下的学生高1.464倍（95%CI=1.2771.677）。女生的积极态度和行为分别是男生的1.424倍（95%CI=1.3291.525）和1.468倍（95%CI=1.2911.669）。母亲拥有大专及以上学历的学生的积极行为比母亲学历为初中及以下的学生高1.347倍（95%CI=1.1471.582）。与父母同住的学生出现积极行为的可能性是其他居住方式学生的1.167倍（95%CI=1.020~1.334）。结构方程模型显示，知识对预防动机、态度和行为的直接效应分别为0.28、0.53和0.10。
大一新生群体对HBV防治的全面认识仍有较大差距。建议高校管理者应更加重视HBV知识教育，并采取多渠道的预防和管理措施。
