Gangi Roberta, Corrias Angelica, Pintus Roberta, Marcialis Maria Antonietta, Fanos Vassilios
School of Pediatrics, University of Cagliari, 09124 Cagliari, Italy.
Department of Surgery, University of Cagliari and Neonatal Intensive Care Unit, AOU di Cagliari, 09124 Cagliari, Italy.
Pediatr Rep. 2022 May 30;14(2):262-275. doi: 10.3390/pediatric14020034.
Recent studies identified pregnancy as a high-risk condition for the development of maternal-fetal complications in the case of the SARS-CoV-2 infection. Therefore, the scientific community is now considering pregnant women a "fragile" category that should be vaccinated with high priority. The number of pregnant women undergoing hospitalization since summer 2021, including Intensive Care Unit admission, is growing, as well as the risk of preterm birth. Evidence from both animals and humans suggest that, similarly to other vaccines routinely administered in pregnancy, COVID-19 vaccines are not crossing the placenta, do not increase the risk of miscarriage, preterm birth, stillbirth, the birth of small gestational age neonates, as well as the risk of congenital abnormalities. To date, the World Health Organization and scientific literature are promoting and encouraging the vaccination of all pregnant and lactating women. The aim of our narrative review is to present the available literature regarding this issue with the aim to provide appropriate answers to the most frequent requests, doubts, and fears that have led many expecting and lactating women not to become vaccinated during this pandemic period.
最近的研究表明，在感染新冠病毒的情况下，怀孕是发生母婴并发症的高风险状况。因此，科学界目前将孕妇视为应优先接种疫苗的“脆弱”群体。自2021年夏季以来，包括入住重症监护病房在内的住院孕妇数量不断增加，早产风险也在上升。来自动物和人类的证据表明，与孕期常规接种的其他疫苗一样，新冠疫苗不会穿过胎盘，不会增加流产、早产、死产、小孕周新生儿出生以及先天性异常的风险。迄今为止，世界卫生组织和科学文献都在推广和鼓励所有孕妇和哺乳期妇女接种疫苗。我们的叙述性综述旨在介绍有关该问题的现有文献，以便为导致许多孕妇和哺乳期妇女在疫情期间未接种疫苗的最常见问题、疑问和担忧提供适当的答案。
