Suppr超能文献

经导航微创经岩下乙状窦前入路选择性肿瘤手术治疗,面神经不重新走行。

Surgical treatment of selected tumors via the navigated minimally invasive presigmoidal suprabulbar infralabyrinthine approach without rerouting of the facial nerve.

机构信息

Department of Neurosurgery, Merheim Hospital, Ostmerheimer Str. 200, 51109, Cologne, Germany.

Faculty of Health, Witten/Herdecke University, Witten, Germany.

出版信息

Neurosurg Rev. 2022 Oct;45(5):3219-3229. doi: 10.1007/s10143-022-01825-0. Epub 2022 Jun 23.

Abstract

The feasibility of a novel skull base approach - the navigated minimally invasive presigmoidal suprabulbar infralabyrinthine approach (NaMIPSI-A) without rerouting of the fallopian canal for selected jugular foramen tumors (JFTs) - has been demonstrated in a neuroanatomical laboratory study. Here, we present our clinical experience with the NaMIPSI-A for selected JFTs, with a particular focus on its efficacy and safety. All patients with JFTs who were treated via the NaMIPSI-A were included in this study. The JFTs were classified according to a modified Fisch classification. The neurological and neuroradiological outcome, the extent of tumor resection, and the approach-related morbidity were examined. Five patients (two women, three men; mean age 57 years, range 48-65) were available. According to the modified Fisch classification, two JFTs were graded as C1, one as De1, and two as De2. Gross total resection (GTR) was achieved in three patients and near-total resection (NTR) in two. Postsurgically, no new neurological deficits and no approach-related morbidity and mortality occurred. One case with a postoperative cerebrospinal fluid leak was managed successfully with lumbar drainage. During the follow-up period (mean 67.6 months, range 12-119 months), tumor recurrence was noted in the NTR group but not in the GTR group. The NaMIPSI-A to the jugular foramen without rerouting of the fallopian canal is highly valuable for selected tumors of the jugular foramen. It is less invasive than other skull base approaches, and it allows safe and complete tumor removal in appropriate patients.

摘要

一种新的颅底入路 - 导航微创经岩下乙状窦前上小脑幕下入路(NaMIPSI-A),无需重新走行输卵管,用于治疗特定颈静脉孔肿瘤(JFTs)的可行性,已在神经解剖学实验室研究中得到证实。在这里,我们报告了我们使用 NaMIPSI-A 治疗选定的 JFT 的临床经验,特别关注其疗效和安全性。所有通过 NaMIPSI-A 治疗的 JFT 患者均纳入本研究。根据改良 Fisch 分类对 JFT 进行分类。检查了神经和神经放射学结果、肿瘤切除程度以及与入路相关的发病率。这项研究纳入了 5 名患者(2 名女性,3 名男性;平均年龄 57 岁,范围 48-65 岁)。根据改良 Fisch 分类,2 个 JFT 为 C1 级,1 个为 De1 级,2 个为 De2 级。3 例患者达到大体全切除(GTR),2 例患者达到近全切除(NTR)。术后无新的神经功能缺损,无与入路相关的发病率和死亡率。1 例术后发生脑脊液漏,经腰椎引流成功治疗。在随访期间(平均 67.6 个月,范围 12-119 个月),NTR 组有肿瘤复发,但 GTR 组无肿瘤复发。不重新走行输卵管的 NaMIPSI-A 到达颈静脉孔对于特定的颈静脉孔肿瘤具有很高的价值。它比其他颅底入路更具侵袭性,并且可以在适当的患者中安全、完全地切除肿瘤。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验