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两种手术入路治疗急性 A 型主动脉夹层的比较:杂交分支术与全弓置换术。

Comparison of two surgical approaches for acute type A aortic dissection: hybrid debranching versus total arch replacement.

机构信息

Department of Cardiovascular Surgery, Fujian Provincial Hospital, Fuzhou, 350001, China.

Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.

出版信息

J Cardiothorac Surg. 2022 Jun 23;17(1):166. doi: 10.1186/s13019-022-01920-9.

Abstract

BACKGROUND

The goal of this study was to determine the clinical outcomes of total arch replacement with frozen elephant trunk surgery and hybrid debranching surgery for acute type A aortic dissection patients.

METHODS

From January 2017 to December 2019, the clinical data of acute type A aortic dissection patients were retrospectively collected and analyzed. There were 142 patients underwent total arch replacement with frozen elephant trunk surgery and 35 patients underwent hybrid debranching surgery.

RESULT

The age, the body mass index and the renal insufficiency of patients in the hybrid group were higher than those in the total arch replacement (TAR) group (all P < 0.01). The operation time, the cardiopulmonary bypass time and the aortic occlusion time of patients in the TAR group were significantly longer than those in the hybrid group (all P < 0.01). Patients in the debranching group had shorter ventilator-assisted breathing time, shorter postoperative hospital stay time and shorter intensive care unit (ICU) stay time. The incidence of pulmonary infection and transient neurological dysfunction were lower, and the transfusions of red blood cells and plasma during the perioperative period were smaller. The survival rates at 2 years were 91.9% and 85.9% in the TAR and hybrid groups, respectively.

CONCLUSION

Hybrid debranching operation is a safe and effective method for acute type A aortic dissection. Compared with TAR surgery, hybrid debranching surgery has the characteristics of less trauma, rapid recovery and lower incidence of complication.

摘要

背景

本研究旨在探讨全主动脉弓置换联合冷冻象鼻手术与杂交分支手术治疗急性 A 型主动脉夹层的临床疗效。

方法

回顾性分析 2017 年 1 月至 2019 年 12 月期间收治的急性 A 型主动脉夹层患者的临床资料,其中行全主动脉弓置换联合冷冻象鼻手术治疗的患者 142 例,行杂交分支手术治疗的患者 35 例。

结果

杂交组患者的年龄、体重指数及肾功能不全发生率均高于全主动脉弓置换组(均 P<0.01);全主动脉弓置换组患者的手术时间、体外循环时间及主动脉阻断时间均长于杂交组(均 P<0.01)。杂交组患者的呼吸机辅助呼吸时间、术后住院时间及 ICU 住院时间均短于全主动脉弓置换组;杂交组患者的肺部感染及一过性神经功能障碍发生率较低,围术期红细胞及血浆输注量较少。全主动脉弓置换组与杂交组患者的 2 年生存率分别为 91.9%、85.9%。

结论

杂交分支手术是治疗急性 A 型主动脉夹层的一种安全有效的方法。与全主动脉弓置换术相比,杂交分支手术具有创伤小、恢复快、并发症发生率低的特点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5291/9229500/d5d08624cf04/13019_2022_1920_Fig1_HTML.jpg

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