Facultad de Ciencias de la Salud, Universidad Científica del Sur, Lima 15067, Peru.
Centro de Excelencia en Investigaciones Económicas y Sociales en Salud, Vicerrectorado de Investigación, Universidad San Ignacio de Loyola, Lima 15024, Peru.
Int J Environ Res Public Health. 2022 Jun 9;19(12):7047. doi: 10.3390/ijerph19127047.
The highest proportion of deaths among patients with cardiovascular diseases is due to ischemic heart disease (IHD), which is the second most common cause of death in Peru. This study aims to measure and identify changes in the temporal trend in mortality from ischemic heart disease in the Peruvian population. An ecological study was carried out with data from individual death records from the Ministry of Health between 2005 and 2017. A death was considered attributable to IHD if it was registered with the codes I20 to I25 of the ICD-10. Crude and adjusted mortality rates for IHD were calculated for the general population by age and according to sex. A joinpoint regression analysis was performed to assess trends in IHD mortality. There were 61,524 deaths due to IHD (55.69% men) from 2005 to 2017. According to the ICD-10, acute myocardial infarction (I21) accounted for the highest proportion of deaths (88.16%), followed by chronic IHD (I25), with 6.53%. In general, a decrease in adjusted IHD mortality rates was found in the general population over time (45.34 in 2005; 22.18 in 2017). By sex, men possessed a 1.5-fold higher rate than women. The highest mortality rates from IHD were found in the natural coastal region (68.55%) and in urban areas (86.43%). A joinpoint regression analysis showed a reduction in the mortality trend over time due to IHD for both the general population and the population when grouped by sex. In conclusion, there was a continuous decrease in mortality rates due to IHD in the Peruvian population between 2005 and 2017. Strategies focused on mitigating the impact of this disease are required and should emphasize the subgroups most likely to die from this cause.
心血管疾病患者的死亡率中，比例最高的是缺血性心脏病（IHD），这也是秘鲁的第二大常见死因。本研究旨在衡量和识别秘鲁人群中缺血性心脏病死亡率的时间趋势变化。采用 2005 年至 2017 年期间卫生部个体死亡记录中的数据进行了一项生态学研究。如果 ICD-10 中的代码 I20 到 I25 记录了死亡，那么就认为该死亡归因于 IHD。计算了一般人群中按年龄和性别分类的 IHD 死亡率的粗死亡率和调整死亡率。使用 joinpoint 回归分析评估 IHD 死亡率的趋势。2005 年至 2017 年期间，共有 61524 例 IHD 死亡（55.69%为男性）。根据 ICD-10，急性心肌梗死（I21）导致的死亡比例最高（88.16%），其次是慢性 IHD（I25），占 6.53%。总体而言，随着时间的推移，一般人群中调整后的 IHD 死亡率呈下降趋势（2005 年为 45.34；2017 年为 22.18）。按性别划分，男性的死亡率是女性的 1.5 倍。IHD 死亡率最高的地区是自然沿海地区（68.55%）和城市地区（86.43%）。joinpoint 回归分析显示，由于 IHD，无论是一般人群还是按性别分组的人群，死亡率趋势都呈下降趋势。总之，2005 年至 2017 年期间，秘鲁人群中 IHD 死亡率持续下降。需要制定针对该疾病影响的策略，这些策略应侧重于最有可能死于该疾病的亚组。
