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抑郁症的整体论:心理治疗过程中抑郁症状的网络。

The Mereology of Depression-Networks of Depressive Symptoms during the Course of Psychotherapy.

机构信息

Department of Clinical Psychology, University of Duisburg-Essen, 45141 Essen, Germany.

Department of Psychiatry, Interdisciplinary Center Psychopathology and Emotion Regulation (ICPE), University Medical Center Groningen, University of Groningen, 9700RB Groningen, The Netherlands.

出版信息

Int J Environ Res Public Health. 2022 Jun 10;19(12):7131. doi: 10.3390/ijerph19127131.

DOI:10.3390/ijerph19127131
PMID:35742380
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9222343/
Abstract

(1) Background: Research has shown that it is important to examine depressive symptoms in the light of the mereology (the ratio between one symptom and the whole disorder). The goal of this study was to examine changes in the symptom interrelations of patients undergoing cognitive behavioral therapy treatment (CBT) via network analyses. (2) Method: Outpatients with depressive symptoms ( = 401) were assessed with the Beck Depression Inventory three times (pretreatment, after 12 sessions, and post-treatment) during CBT. Gaussian graphical models were used to estimate the relationships among symptoms. (3) Results: The severity of depressive symptoms significantly decreased over the course of therapy, but connectivity in the networks significantly increased. Communities of symptoms changed during treatment. The most central and predictable symptom was worthlessness at baseline and after 12 sessions, and loss of energy and self-dislike at post-treatment. (4) Conclusion: The results indicate that the severity of depressive symptoms decreased during cognitive behavior therapy, while network connectivity increased. Furthermore, the associations among symptoms and their centrality changed during the course of therapy. Future studies may investigate individual differences and their impact on the planning of psychotherapeutic treatment.

摘要

(1) 背景:研究表明,从整体论(一个症状与整个疾病之间的比例)的角度来检查抑郁症状很重要。本研究的目的是通过网络分析来检查接受认知行为治疗(CBT)的患者症状相互关系的变化。

(2) 方法:在 CBT 期间,对有抑郁症状的门诊患者(=401)使用贝克抑郁量表进行了三次评估(治疗前、12 次治疗后和治疗后)。使用高斯图形模型来估计症状之间的关系。

(3) 结果:抑郁症状的严重程度在治疗过程中显著下降,但网络的连通性显著增加。症状的社区在治疗过程中发生了变化。基线时和 12 次治疗后最中心和最可预测的症状是无价值感,而治疗后是精力丧失和自我厌恶。

(4) 结论:结果表明,在认知行为治疗过程中,抑郁症状的严重程度降低,而网络连通性增加。此外,症状之间的关联及其中心性在治疗过程中发生了变化。未来的研究可能会调查个体差异及其对心理治疗计划的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92fe/9222343/a79a3253466b/ijerph-19-07131-g002a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92fe/9222343/5724ec60c44b/ijerph-19-07131-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92fe/9222343/a79a3253466b/ijerph-19-07131-g002a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92fe/9222343/5724ec60c44b/ijerph-19-07131-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92fe/9222343/a79a3253466b/ijerph-19-07131-g002a.jpg

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