Vellinga Remco, Valk Beatrijs I, Absalom Anthony R, Struys Michel M R F, Barends Clemens R M
Department of Anesthesiology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands.
Department of Anesthesiology, University Medical Center Göttingen, 37075 Göttingen, Germany.
J Clin Med. 2022 Jun 17;11(12):3493. doi: 10.3390/jcm11123493.
New anaesthetic drugs and new methods to administer anaesthetic drugs are continually becoming available, and the development of new PK-PD models furthers the possibilities of using arget controlled infusion (TCI) for anaesthesia. Additionally, new applications of existing anaesthetic drugs are being investigated. This review describes the current situation of anaesthetic drug development and methods of administration, and what can be expected in the near future.
新的麻醉药物和麻醉药物给药新方法不断涌现,新的药代动力学-药效学(PK-PD)模型的发展进一步拓展了将靶控输注(TCI)用于麻醉的可能性。此外,现有麻醉药物的新应用也在研究之中。本综述描述了麻醉药物研发及给药方法的现状,以及近期的发展趋势。