Shangguan Wenfeng, Xu Gang, Wang Xin, Zhang Nan, Liu Xingpeng, Li Guangping, Tse Gary, Liu Tong
Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease, Department of Cardiology, Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University, Tianjin 300211, China.
Department of Heart Center, Beijing Chaoyang Hospital, Capital Medical University, 8th Gongtinanlu Rd., Chaoyang District, Beijing 100020, China.
J Clin Med. 2022 Jun 20;11(12):3549. doi: 10.3390/jcm11123549.
Refractory ventricular tachycardia (VT) often occurs in the context of organic heart disease. It is associated with significantly high mortality and morbidity rates. Antiarrhythmic drugs and catheter ablation represent the two main treatment options for refractory VT, but their use can be associated with inadequate therapeutic responses and procedure-related complications. Stereotactic body radiotherapy (SBRT) is extensively applied in the precision treatment of solid tumors, with excellent therapeutic responses. Recently, this highly precise technology has been applied for radioablation of VT, and its early results demonstrate a favorable safety profile. This review presents the potential value of SBRT in refractory VT.
难治性室性心动过速(VT)常发生于器质性心脏病背景下。它与显著较高的死亡率和发病率相关。抗心律失常药物和导管消融是难治性VT的两种主要治疗选择,但使用这些方法可能会出现治疗反应不足及与手术相关的并发症。立体定向体部放疗(SBRT)广泛应用于实体肿瘤的精准治疗,疗效良好。最近,这项高精度技术已被应用于VT的射频消融,其早期结果显示出良好的安全性。本文综述了SBRT在难治性VT中的潜在价值。