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冠状病毒中的重组,以 SARS-CoV-2 为例。

Recombination in Coronaviruses, with a Focus on SARS-CoV-2.

机构信息

North-Western Tuscany Blood Bank, Pisa University Hospital, 56124 Pisa, Italy.

Department of Medicine and Surgery, University of Insubria, 21100 Varese, Italy.

出版信息

Viruses. 2022 Jun 7;14(6):1239. doi: 10.3390/v14061239.

Abstract

Recombination is a common evolutionary tool for RNA viruses, and coronaviruses are no exception. We review here the evidence for recombination in SARS-CoV-2 and reconcile nomenclature for recombinants, discuss their origin and fitness, and speculate how recombinants could make a difference in the future of the COVID-19 pandemics.

摘要

重组是 RNA 病毒常见的进化工具,冠状病毒也不例外。本文回顾了 SARS-CoV-2 中重组的证据,调和了重组体的命名法,讨论了它们的起源和适应性,并推测了重组体在未来 COVID-19 大流行中可能会产生怎样的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/88f6/9228924/5fe7d582505c/viruses-14-01239-g001.jpg

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