Graff-Radford N R, Godersky J C
Neurology. 1987 May;37(5):868-71. doi: 10.1212/wnl.37.5.868.
Nineteen patients with idiopathic normal pressure hydrocephalus (NPH) were treated with intraventricular shunts. Ten of the 14 who improved and 14 of the total group had systemic hypertension. The prevalence of hypertension in both the improved and whole NPH groups was significantly greater than in a control group with dementia (N = 122) and the published prevalence of hypertension in the US population for this age group. Four possible mechanisms for this association are discussed.
19例特发性正常压力脑积水(NPH)患者接受了脑室内分流治疗。病情改善的14例患者中有10例以及全部患者中的14例患有系统性高血压。病情改善组和整个NPH组的高血压患病率显著高于痴呆对照组(N = 122)以及该年龄组美国人群中已公布的高血压患病率。文中讨论了这种关联的四种可能机制。