Pararas Nikolaos, Foukas Periklis G, Pikoulis Andreas, Bagias George, Papakonstantinou Dimitris, Pappa Vassiliki, Nastos Konstantinos, Pikoulis Emmanouil
Surgical Department, Dr Sulaiman Al Habib Hospital, Riyadh 12987, Saudi Arabia.
Second Department of Pathology, National and Kapodistrian University of Athens, Attikon University Hospital, 12462 Athens, Greece.
Mol Clin Oncol. 2022 May 25;17(1):115. doi: 10.3892/mco.2022.2548. eCollection 2022 Jul.
Lymphoma is known to be a systemic lymphoproliferative malignancy, which is divided into two subtypes: Hodgkin lymphoma and non-Hodgkin lymphoma. Non-Hodgkin lymphoma originates from nodal and extranodal sites. In the staging of non-Hodgkin lymphoma, the liver is implicated in 40% of cases; however, primary liver non-Hodgkin lymphoma represents <1% of all non-Hodgkin lymphoma cases. Because of its rarity, it is not usually considered in the differential diagnosis of patients that present with jaundice. Since the first case of primary non-Hodgkin lymphoma of the extra-hepatic bile ducts was presented, only 42 similar cases have been reported in the English literature. The present case report describes a rare case of non-Hodgkin lymphoma of the common hepatic duct, which presented with obstructive jaundice and represented a complex differential diagnostic issue.
淋巴瘤是一种全身性淋巴增殖性恶性肿瘤,分为两种亚型:霍奇金淋巴瘤和非霍奇金淋巴瘤。非霍奇金淋巴瘤起源于淋巴结和结外部位。在非霍奇金淋巴瘤的分期中,40%的病例累及肝脏;然而,原发性肝脏非霍奇金淋巴瘤占所有非霍奇金淋巴瘤病例的比例不到1%。由于其罕见性,在出现黄疸的患者的鉴别诊断中通常不会考虑到它。自从第一例肝外胆管原发性非霍奇金淋巴瘤被报道以来,英文文献中仅报道了42例类似病例。本病例报告描述了一例罕见的肝总管非霍奇金淋巴瘤,该病例表现为梗阻性黄疸,是一个复杂的鉴别诊断问题。