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人脑电刺激和磁刺激的不同作用部位。

Different sites of action of electrical and magnetic stimulation of the human brain.

作者信息

Day B L, Thompson P D, Dick J P, Nakashima K, Marsden C D

出版信息

Neurosci Lett. 1987 Mar 20;75(1):101-6. doi: 10.1016/0304-3940(87)90083-8.

DOI:10.1016/0304-3940(87)90083-8
PMID:3574763
Abstract

The latency of the surface recorded electromyographic response to either an electrical or magnetic stimulus applied to the scalp has been measured in the first dorsal interosseous and abductor pollicis brevis muscles of 3 subjects. In the contracting muscle the response latency to the magnetic stimulus was longer by 1.4-2.7 ms compared to the electrical stimulus. Poststimulus time histograms of the firing of single motor units of first dorsal interosseous muscle were studied in 4 subjects. The first period of increased probability of firing of the single motor units showed a similar latency difference (mean 2.8 ms) to the two modes of stimulation. It is concluded that the extra delay to magnetic stimulation is consumed in central motor pathways. This implies that the two modes of stimulation activate the brain at different sites. It is suggested that the magnetic stimulus excites the corticospinal neurones transynaptically, whereas the electrical stimulus excites these neurones directly.

摘要

在3名受试者的第一背侧骨间肌和拇短展肌中,测量了对施加于头皮的电刺激或磁刺激的表面记录肌电图反应的潜伏期。在收缩的肌肉中,与电刺激相比,磁刺激的反应潜伏期长1.4 - 2.7毫秒。在4名受试者中研究了第一背侧骨间肌单个运动单位放电的刺激后时间直方图。单个运动单位放电概率增加的第一个时期显示出与两种刺激模式相似的潜伏期差异(平均2.8毫秒)。得出的结论是,磁刺激的额外延迟消耗在中枢运动通路中。这意味着两种刺激模式在不同部位激活大脑。有人提出,磁刺激通过突触间激发皮质脊髓神经元,而电刺激则直接激发这些神经元。

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1
Different sites of action of electrical and magnetic stimulation of the human brain.人脑电刺激和磁刺激的不同作用部位。
Neurosci Lett. 1987 Mar 20;75(1):101-6. doi: 10.1016/0304-3940(87)90083-8.
2
Responses in small hand muscles from magnetic stimulation of the human brain.人脑磁刺激引起的手部小肌肉反应。
J Physiol. 1987 Jul;388:397-419. doi: 10.1113/jphysiol.1987.sp016621.
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[Characteristics of electrical discharges by transcranial cortex stimulation activated motor units of the hand muscles of the human].[经颅皮层刺激激活人类手部肌肉运动单位的放电特征]
EEG EMG Z Elektroenzephalogr Elektromyogr Verwandte Geb. 1988 Dec;19(4):216-21.
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Effect of digital nerve stimuli on responses to electrical or magnetic stimulation of the human brain.指神经刺激对人脑电刺激或磁刺激反应的影响。
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Corticobulbar and corticospinal projections to neck muscle motoneurons in man. A functional study with magnetic and electric transcranial brain stimulation.
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Latency of effects evoked by electrical and magnetic brain stimulation in lower limb motoneurones in man.人体下肢运动神经元对电刺激和磁刺激所诱发反应的潜伏期
J Physiol. 1995 May 1;484 ( Pt 3)(Pt 3):791-802. doi: 10.1113/jphysiol.1995.sp020704.
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Direct comparison of corticospinal volleys in human subjects to transcranial magnetic and electrical stimulation.人体受试者中皮质脊髓冲动与经颅磁刺激和电刺激的直接比较。
J Physiol. 1993 Oct;470:383-93. doi: 10.1113/jphysiol.1993.sp019864.
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Some experiences of techniques for stimulation of the human cerebral motor cortex through the scalp.通过头皮刺激人类大脑运动皮层的技术的一些经验。
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Transcranial electrical and magnetic motor cortex stimulation: studies in intact man.经颅电刺激和磁刺激运动皮层:对正常人的研究。
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Silent period evoked by transcranial stimulation of the human cortex and cervicomedullary junction.经颅刺激人类皮层和颈髓交界处诱发的静息期。
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