Ueda Shota, Nakane Keita, Namiki Sanae, Takeuchi Yasumichi, Kawase Makoto, Takeuchi Shinichi, Kawase Kota, Nakai Chie, Kato Daiki, Takai Manabu, Iinuma Koji, Tsuchiya Tomohiro, Miyazaki Tatsuhiko, Koie Takuya
The Department of Urology, Gifu University Graduate School of Medicine.
The Department of Pathology, Gifu University School of Medicine.
Hinyokika Kiyo. 2022 May;68(5):139-143. doi: 10.14989/ActaUrolJap_68_5_139.
A 40-year-old Japanese female was referred to our institution with a high serum lactate dehydrogenase level. Computed tomography (CT) showed a large right adrenal tumor, 14 cm in size without distant metastases. The patient was clinically diagnosed with T2N0M0 adrenocortical carcinoma and underwent right adrenalectomy. The pathological diagnosis was adrenocortical carcinoma with negative surgical margin. The patient was administered mitotane for 2 years as adjuvant therapy. Subsequently, CT revealed asynchronous multiple metastases, including liver, lung, left kidney, and right acetabulum. The patient received 15 courses of EDP (a combination of etoposide, doxorubicin, and cisplatin) plus mitotane therapy, and had stable disease without new lesions.
一名40岁的日本女性因血清乳酸脱氢酶水平升高被转诊至我院。计算机断层扫描（CT）显示右侧肾上腺有一个大肿瘤，大小为14厘米，无远处转移。该患者临床诊断为T2N0M0肾上腺皮质癌，并接受了右侧肾上腺切除术。病理诊断为肾上腺皮质癌，手术切缘阴性。患者接受了2年的米托坦辅助治疗。随后，CT显示出现包括肝脏、肺、左肾和右髋臼在内的异时性多发转移。该患者接受了15个疗程的EDP（依托泊苷、阿霉素和顺铂联合）加米托坦治疗，病情稳定，无新病灶。
