Mechanical Engineering, Johns Hopkins University, USA.
Otolaryngology HNS, Johns Hopkins University, Ross 830, 720 Rutland Ave, Baltimore, MD 21205, USA.
Lab Chip. 2022 Jul 12;22(14):2707-2713. doi: 10.1039/d2lc00312k.
Ionic transistors can be used to modulate ionic current in a way that is analogous to their electronic counterparts. An ionic transistor can reversibly change its ionic conduction to control ionic current by injecting electrical charges. To facilitate its applications in biomedical devices (, controlled drug delivery, rectification of ionic current, and signal processing), an ionic transistor should maintain high performance of ionic current control within physiological solutions (, 0.9% NaCl) for long durations. Here, we introduce an ionic transistor using cation and anion exchange membranes (CEM and AEM). It could impose a 10× impedance change in a channel filled with 0.9% NaCl solution and we observed a stable modulation of ionic current throughout a test of 1000 cycles of on/off switching of the ionic transistor.
离子晶体管可以用来调制离子电流，其方式类似于电子晶体管。离子晶体管可以通过注入电荷来可逆地改变其离子传导，从而控制离子电流。为了促进其在生物医学设备中的应用（如，控制药物输送、离子电流整流和信号处理），离子晶体管应该在生理溶液（如，0.9% NaCl）中长时间保持对离子电流的高性能控制。在这里，我们介绍了一种使用阳离子交换膜和阴离子交换膜的离子晶体管。它可以在充满 0.9% NaCl 溶液的通道中施加 10 倍的阻抗变化，并且我们观察到在离子晶体管的开/关切换测试 1000 个循环中，离子电流的稳定调制。
