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尼日利亚西南部奥索博的貌似健康的中学生原发性高血压伴靶器官损害。

Primary Hypertension with Target Organ Damage among Apparently Healthy Secondary School Students in Osogbo, South-Western Nigeria.

机构信息

Department of Paediatrics, Evercare International Multi-Specialty Hospital, Lekki Phase 1, Lagos State, Nigeria.

Department of Paediatrics, College of Health Sciences, LAUTECH, Ogbomoso, Oyo State, Nigeria.

出版信息

West Afr J Med. 2022 Jun 24;39(6):573-579.

Abstract

INTRODUCTION

In recent times, there has been an increase in the frequency of hypertension among young people which is contributing globally to the increase in cardiovascular morbidity and mortality in adults.

OBJECTIVE

The aim of this study was therefore to determine the prevalence of primary hypertension and its risk factors among apparently healthy secondary school students in Osogbo, southwestern Nigeria.

METHODS

A school-based cross-sectional study of a total of 404 secondary school students in Osogbo city. Following informed parental consents of all the students involved in the study, blood pressure (BP) measurements were taken at 2 different visits by auscultation after a negative urine dip stick test result (thus excluding haematuria or proteinuria) in every subject before each BP was measured.

RESULTS

The overall prevalence of hypertension and prehypertension in this study was 3.5% (n = 14) and 6.2% (n = 25), respectively. Obesity, consumption of extra - uncooked salt, high parental education and attendance of privately-owned secondary schools were identified risk factors associated with elevated BP. Seven (29%) of 24 subjects with hypertension had features of left ventricular hypertrophy (an evidence of target organ damage) on echocardiography and electrocardiography. All subjects with elevated BP had normal renal scan.

CONCLUSION

Hypertension with features of target organ damage exists among adolescents. No known primary aetiologies were found among the hypertensive adolescents in the study and thus they were all deemed to have essential hypertension.

摘要

简介

近年来,年轻人高血压的发病率有所上升,这导致全球成年人的心血管发病率和死亡率上升。

目的

本研究旨在确定尼日利亚西南部奥索戈博市的健康中学生原发性高血压及其危险因素的流行情况。

方法

对奥索戈博市的 404 名中学生进行了一项基于学校的横断面研究。在所有参与研究的学生的父母都同意后,对每个学生进行了两次血压测量,在进行第一次血压测量前,先进行尿液干化学试纸检测(排除血尿或蛋白尿),如果结果为阴性,再进行血压测量。

结果

本研究中高血压和高血压前期的总体患病率分别为 3.5%(n=14)和 6.2%(n=25)。肥胖、额外摄入未煮熟的盐、高父母教育程度和就读私立中学是与血压升高相关的危险因素。24 名高血压患者中有 7 名(29%)在超声心动图和心电图上有左心室肥厚的特征(靶器官损害的证据)。所有血压升高的患者的肾脏扫描均正常。

结论

青少年中存在高血压伴靶器官损害。在研究中的高血压青少年中没有发现已知的原发性病因,因此他们都被认为患有原发性高血压。

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