van Spreeuwel J P, Lindeman J, Bax R, Elbers H J, Sybrandy R, Meijer C J
Pathol Annu. 1987;22 Pt 1:55-65.
To determine the prevalence of Campylobacter fetus subspecies jejuni-associated appendicitis, we studied, retrospectively, by means of immunohistochemistry, the appendectomy specimens of 116 consecutive patients, operated upon because of suspected acute appendicitis. We found immunohistochemical evidence of Campylobacter fetus subspecies jejuni infection in three patients. These findings were confirmed by electron microscopy. Based upon these three cases and five additional appendectomy specimens from patients with Campylobacter enteritis diagnosed by stool cultures, the clinical and histologic picture of Campylobacter-associated appendicitis is described. It is concluded that Campylobacter infection may present with an acute appendicitis-like clinical picture. In contrast with acute phlegmonous appendicitis, the histologic abnormalities in Campylobacter-associated appendicitis are limited to the appendiceal mucosa.
为确定胎儿弯曲菌空肠亚种相关性阑尾炎的患病率，我们采用免疫组织化学方法，对116例因疑似急性阑尾炎接受手术的连续患者的阑尾切除标本进行了回顾性研究。我们在3例患者中发现了胎儿弯曲菌空肠亚种感染的免疫组织化学证据。这些发现通过电子显微镜得到了证实。基于这3例病例以及另外5例经粪便培养确诊为弯曲菌肠炎患者的阑尾切除标本，描述了弯曲菌相关性阑尾炎的临床和组织学表现。得出的结论是，弯曲菌感染可能呈现出类似急性阑尾炎的临床表现。与急性蜂窝织炎性阑尾炎不同，弯曲菌相关性阑尾炎的组织学异常仅限于阑尾黏膜。
