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深龋磨牙伴牙本质发育不全(MIH)缺陷的活髓治疗结局:一项随机临床试验。

Outcome of vital pulp therapy in deeply carious molars affected with molar incisor hypomineralisation (MIH) defects: a randomized clinical trial.

机构信息

Department of Preventive Dentistry, Faculty of Dentistry, Jordan University of Science and Technology, PO Box 3030, Irbid, 22110, Jordan.

出版信息

Eur Arch Paediatr Dent. 2022 Aug;23(4):587-599. doi: 10.1007/s40368-022-00722-w. Epub 2022 Jun 25.

Abstract

PURPOSE

To evaluate clinical and radiographic outcomes of vital pulp therapy (VPT) in deeply carious young permanent first molars (PFM) affected with MIH over 24 months.

METHODS

In this prospective randomized clinical trial, n = 50 children with deeply carious young PFM affected with MIH, and diagnosed with reversible or irreversible pulpitis were randomized into 2 groups: indirect pulp treatment (IPT) and pulpotomy (partial or complete). Teeth were followed up clinically and radiographically for 24 months. Statistical analysis was done using Chi-square test; P ≤ 0.05 was considered significant.

RESULTS

A total of  n = 50 teeth/patients (n = 26 females (52%), n = 24 males (48%)) were included, and 14 upper and 36 lower PFM were treated. Mean age was 11 ± 3.2 years. Clinical and radiographic success rates were: 96% for IPT, 90% for PP and 82% for CP (and 86% for both types of pulpotomy combined) over 24 months. There were no significant differences in outcomes between treatment groups. Age, gender and tooth location/jaw were found to have no statistically significant difference in outcomes among treatment groups, nor did pulpal status or root maturity, regardless of type of VPT and follow up period.

CONCLUSIONS

VPT is a valid treatment option in deeply carious young permanent first molars affected with MIH over 24 months. IPT had a higher clinical and radiographic success rate (96%) than partial or cervical pulpotomy (total 86%), but the difference was not statistically significant. Future randomized clinical trials on VPT for teeth affected with MIH are recommended with larger sample size and longer follow-up.

摘要

目的

评估在 24 个月的时间内,患有 MIH 的深龋年轻恒牙(PFM)接受活髓保存治疗(VPT)的临床和影像学效果。

方法

在这项前瞻性随机临床试验中,将 n=50 名患有 MIH 的深龋年轻 PFM 且患有可逆或不可逆牙髓炎的儿童随机分为 2 组:间接牙髓治疗(IPT)和牙髓切断术(部分或完全)。对牙齿进行了 24 个月的临床和影像学随访。使用卡方检验进行统计学分析;P≤0.05 被认为具有统计学意义。

结果

共纳入 n=50 颗牙/患者(n=26 名女性(52%),n=24 名男性(48%)),共治疗了 14 颗上颌 PFM 和 36 颗下颌 PFM。平均年龄为 11±3.2 岁。IPT 的临床和影像学成功率为 96%,PP 为 90%,CP 为 82%(两种类型的牙髓切断术的总成功率为 86%),24 个月时的成功率为 96%。24 个月时,各组之间的治疗效果无显著差异。在治疗组之间,无论 VPT 类型和随访时间如何,年龄、性别和牙齿位置/颌骨、牙髓状态或根成熟度均无统计学意义。

结论

在 24 个月的时间内,VPT 是一种治疗深龋年轻恒牙伴 MIH 的有效方法。IPT 的临床和影像学成功率(96%)高于部分或颈髓切断术(总成功率 86%),但差异无统计学意义。建议进行更大样本量和更长随访时间的关于 VPT 治疗 MIH 牙的随机临床试验。

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