Department of Orthopedic Surgery, the Fourth Medical Center of Chinese PLA General Hospital, Beijing, China.
Department of Orthopedic Surgery, the Fourth Medical Center of Chinese PLA General Hospital, Beijing, China.
World Neurosurg. 2022 Sep;165:e457-e468. doi: 10.1016/j.wneu.2022.06.083. Epub 2022 Jun 22.
The objective of this study was to compare the safety and clinical efficacy of full-endoscopic lumbar interbody fusion (FE-LIF) and minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF).
A total of 70 patients with single-level lumbar degenerative diseases underwent FE-LIF or MIS-TLIF with a tubular retractor system from August 2018 to August 2020. Postoperatively, the efficacy and safety were compared using several clinical and radiological indices.
A total of 32 patients underwent FE-LIF and 38 received MIS-TLIF with a tubular retractor system, and all patients had no apparent complications. The FE-LIF group had higher radiation exposure, longer operation time, and less bleeding than the MIS-TLIF group (P < 0.05). Postoperative lumbar magnetic resonance imaging showed that the nerve decompression was sufficient. The pain in the lower back and legs was significantly relieved, and the Oswestry Disability Index (ODI) score was greatly improved after surgery (P < 0.01) in both the groups. The sensory and motor functions of nerve roots were remarkably recovered in both the groups at the 1-year follow-up (P < 0.05), and there was no significant difference in MacNab scores between the 2 groups. As per Mannion's fusion classification, the interbody fusion rate was significantly better in the FE-LIF group than in the MIS-TLIF group.
FE-LIF, which is safe, effective, and minimally invasive, exhibits the same clinical efficacy as MIS-TLIF but with longer operation time and increased radiation exposure.
本研究旨在比较全内窥镜腰椎体间融合术(FE-LIF)和微创经椎间孔腰椎体间融合术(MIS-TLIF)的安全性和临床疗效。
2018 年 8 月至 2020 年 8 月,共 70 例单节段腰椎退变性疾病患者接受管状牵开器系统辅助下的 FE-LIF 或 MIS-TLIF 治疗。术后采用多项临床和影像学指标比较疗效和安全性。
共 32 例患者接受 FE-LIF,38 例患者接受 MIS-TLIF,两组均无明显并发症。FE-LIF 组的辐射暴露、手术时间和出血量均低于 MIS-TLIF 组(P<0.05)。术后腰椎磁共振成像显示神经减压充分。两组患者术后腰痛和下肢痛均明显缓解,Oswestry 功能障碍指数(ODI)评分均显著改善(P<0.01)。两组患者神经根感觉和运动功能在术后 1 年随访时均显著恢复(P<0.05),两组 MacNab 评分无显著差异。根据 Mannion 的融合分类,FE-LIF 组的椎间融合率明显优于 MIS-TLIF 组。
FE-LIF 安全、有效、微创,与 MIS-TLIF 具有相同的临床疗效,但手术时间更长,辐射暴露增加。