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基于分组的盆底肌训练是治疗老年女性尿失禁更具成本效益的方法:一项随机试验的经济分析

Group-based pelvic floor muscle training is a more cost-effective approach to treat urinary incontinence in older women: economic analysis of a randomised trial.

作者信息

Cacciari Licia P, Kouakou Christian Rc, Poder Thomas G, Vale Luke, Morin Mélanie, Mayrand Marie-Hélène, Tousignant Michel, Dumoulin Chantale

机构信息

School of Rehabilitation, Faculty of Medicine, Université de Montréal and Research Center of the Institut universitaire de gériatrie de Montréal, Montréal, Canada.

Département d'Économique, Université de Sherbrooke, Sherbrooke, Canada.

出版信息

J Physiother. 2022 Jul;68(3):191-196. doi: 10.1016/j.jphys.2022.06.001. Epub 2022 Jun 23.

Abstract

QUESTION(S): How cost-effective is group-based pelvic floor muscle training (PFMT) for treating urinary incontinence in older women?

DESIGN

Economic evaluation conducted alongside an assessor-blinded, multicentre randomised non-inferiority trial with 1-year follow-up.

PARTICIPANTS

A total of 362 women aged ≥ 60 years with stress or mixed urinary incontinence.

INTERVENTION

Twelve weekly 1-hour PFMT sessions delivered individually (one physiotherapist per woman) or in groups (one physiotherapist per eight women).

OUTCOME MEASURES

Urinary incontinence-related costs per woman were estimated from a participant and provider perspective over 1 year in Canadian dollars, 2019. Effectiveness was based on reduction in leakage episodes and quality-adjusted life years. Incremental cost-effectiveness ratios and net monetary benefit were calculated for each of the effectiveness outcomes and perspectives.

RESULTS

Both group-based and individual PFMT were effective in reducing leakage and promoting gains in quality-adjusted life years. Furthermore, group-based PFMT was ≥ 60% less costly than individual treatment, regardless of the perspective studied: -$914 (95% CI -970 to -863) from the participant's perspective and -$509 (95% CI -523 to -496) from the provider's perspective. Differences in effects between study arms were minor and negligible. Adherence to treatment was high, with low loss to follow-up and no between-group differences.

CONCLUSION

Compared with standard individual PFMT, group-based PFMT was less costly and as clinically effective and widely accepted. These results indicate that patients and healthcare decision-makers should consider group-based PFMT to be a cost-effective first-line treatment option for urinary incontinence.

TRIAL REGISTRATION

ClinicalTrials.govNCT02039830.

摘要

问题

基于小组的盆底肌训练(PFMT)治疗老年女性尿失禁的成本效益如何?

设计

在一项评估者盲法、多中心随机非劣效性试验的基础上进行经济评估,并随访1年。

参与者

共有362名年龄≥60岁的压力性或混合性尿失禁女性。

干预措施

每周进行12次,每次1小时的PFMT训练,训练方式为个体训练(每位女性配备一名物理治疗师)或小组训练(每八名女性配备一名物理治疗师)。

结局指标

从参与者和提供者的角度,以2019年加拿大元为单位,估算每位女性1年内与尿失禁相关的成本。有效性基于漏尿次数的减少和质量调整生命年。针对每个有效性结局和角度计算增量成本效益比和净货币效益。

结果

基于小组的PFMT和个体PFMT在减少漏尿和提高质量调整生命年方面均有效。此外,无论从哪个研究角度来看,基于小组的PFMT成本都比个体治疗低≥60%:从参与者角度看为 -914加元(95%CI -970至 -863),从提供者角度看为 -509加元(95%CI -523至 -496)。研究组之间的效果差异微小且可忽略不计。治疗依从性高,随访失访率低,且组间无差异。

结论

与标准的个体PFMT相比,基于小组的PFMT成本更低,临床效果相同且被广泛接受。这些结果表明,患者和医疗保健决策者应将基于小组的PFMT视为尿失禁具有成本效益的一线治疗选择。

试验注册

ClinicalTrials.govNCT02039830

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