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接种 COVID-19 疫苗后出现的类狼疮样皮肤反应。

Cutaneous lupus-erythematosus-like reaction arising after COVID-19 vaccination.

机构信息

Department of Dermatology, Walter Reed National Military Medical Center, Bethesda, Maryland, USA.

出版信息

J Cutan Pathol. 2022 Nov;49(11):943-946. doi: 10.1111/cup.14281. Epub 2022 Aug 4.

Abstract

Multiple adverse cutaneous reactions have been described following vaccination against COVID-19. This case report describes a reaction to the Pfizer-BioNTech (BNT162b2) vaccine that histopathologically resembles cutaneous lupus erythematosus with vacuolar interface alteration, superficial to mid-dermal perivascular and periadnexal lymphocytic infiltrate with clusters of CD123 cells, and mildly increased dermal mucin.

摘要

接种 COVID-19 疫苗后出现了多种不良反应。本病例报告描述了一例对辉瑞-生物科技(BNT162b2)疫苗的反应,其组织病理学表现类似于具有空泡界面改变的红斑狼疮,真皮浅层至中层血管周围和附属器周围淋巴细胞浸润,伴有 CD123 细胞簇,真皮粘蛋白轻度增加。

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