Faupel-Badger Jessica M, Vogel Amanda L, Hussain Shadab F, Austin Christopher P, Hall Matthew D, Ness Elizabeth, Sanderson Philip, Terse Pramod S, Xu Xin, Balakrishnan Krishna, Patnaik Samarjit, Marugan Juan J, Rudloff Udo, Ferrer Marc
National Institutes of Health, National Center for Advancing Translational Sciences, Bethesda, MD, USA.
Flagship Pioneering, Cambridge, MA, USA.
J Clin Transl Sci. 2022 Mar 21;6(1):e66. doi: 10.1017/cts.2022.374. eCollection 2022.
There are numerous examples of translational science innovations addressing challenges in the translational process, accelerating progress along the translational spectrum, and generating solutions relevant to a wide range of human health needs. Examining these successes through an education lens can identify core principles and effective practices that lead to successful translational outcomes. The National Center for Advancing Translational Sciences (NCATS) is identifying and teaching these core principles and practices to a broad audience via online courses in translational science which teach from case studies of NCATS-led or supported research initiatives. In this paper, we share our approach to the design of these courses and offer a detailed description of our initial course, which focused on a preclinical drug discovery and development project spanning academic and government settings. Course participants were from a variety of career stages and institutions. Participants rated the course high in overall value to them and in providing a unique window into the translational science process. We share our model for course development as well as initial findings from the course evaluation with the goal of continuing to stimulate development of novel education activities teaching foundational principles in translational science to a broad audience.
有许多转化科学创新的例子,它们应对转化过程中的挑战,加速沿转化谱系的进展,并生成与广泛的人类健康需求相关的解决方案。通过教育视角审视这些成功案例,可以确定导致成功转化成果的核心原则和有效做法。美国国立转化医学推进中心(NCATS)正在通过转化科学在线课程,向广大受众识别并传授这些核心原则和做法,这些课程从NCATS牵头或支持的研究项目的案例研究中汲取经验进行教学。在本文中,我们分享这些课程的设计方法,并详细介绍我们的初始课程,该课程聚焦于一个跨越学术和政府机构的临床前药物发现与开发项目。课程参与者来自不同的职业阶段和机构。参与者对该课程给予了高度评价,认为其对他们具有很高的整体价值,并为了解转化科学过程提供了独特视角。我们分享课程开发模式以及课程评估的初步结果,目的是继续推动新颖教育活动的发展,向广大受众传授转化科学的基础原则。