老年药学中一个值得进行循证干预的令人担忧的趋势。
A concerning trend in geriatric pharmacy that merits evidence-based intervention.
作者信息
Hughes Hunter Merritt, Nizami Hamasah, Polanco Juan Sebastian, Poulson Jessica, Cai Alice, Mittal Rea, Su Lilly, Jain Pranjal, Jain Rohit
机构信息
School of Medicine, Pennsylvania State College of Medicine, Hershey, Pennsylvania.
School of Medicine, American University of Integrative Sciences, St. Michael, Barbados.
出版信息
Proc (Bayl Univ Med Cent). 2022 May 23;35(4):480-484. doi: 10.1080/08998280.2022.2074211. eCollection 2022.
The effects of polypharmacy on geriatric populations are an emerging concern that merits more exploration. The primary goal of this review was to evaluate the current body of knowledge on polypharmacy and explore the preventive and corrective measures to avoid negative outcomes. Even if a medication has an appropriate indication, polypharmacy in the geriatric population is associated with an increased risk of drug-drug or drug-condition interactions. Recent efforts to prevent polypharmacy include the development of interprofessional teams in clinics dedicated to medication review and reconciliation, deprescription plans aimed to safely discontinue potentially inappropriate medications, and inpatient screening tools that provide prescribing recommendations. In conclusion, polypharmacy affects a high percentage of the geriatric population. Current efforts to address and prevent polypharmacy are ongoing but have not been widely adopted.
多重用药对老年人群的影响是一个新出现的问题，值得进一步探讨。本综述的主要目的是评估当前关于多重用药的知识体系，并探索预防和纠正措施以避免不良后果。即使一种药物有适当的适应症，老年人群中的多重用药仍与药物相互作用或药物与疾病相互作用的风险增加有关。近期预防多重用药的努力包括在专门进行药物审查与核对的诊所中组建跨专业团队、旨在安全停用潜在不适当药物的减药计划，以及提供处方建议的住院筛查工具。总之，多重用药影响着很大比例的老年人群。目前针对多重用药问题所采取的应对和预防措施正在进行中，但尚未得到广泛应用。
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