单倍体相合干细胞移植成功治疗成人急性T细胞白血病。
Successfully treated acute adult T-cell leukemia with haploidentical stem cell transplantation.
作者信息
Thurlapati Aswani, Graham Christopher, Boudreaux Kyle, Wangjam Tamna
机构信息
Department of Internal Medicine, LSU Health Shreveport, Shreveport, Louisiana.
Department of Hematology and Oncology, LSU Health Shreveport, Shreveport, Louisiana.
出版信息
Proc (Bayl Univ Med Cent). 2022 Apr 12;35(4):557-559. doi: 10.1080/08998280.2022.2058901. eCollection 2022.
Abstract
Adult T-cell leukemia-lymphoma caused by human T-lymphotropic virus type 1 is a rare and aggressive tumor with high morbidity and mortality. Historically it has been treated with chemotherapy, but more recent studies suggest improvement in survival with the combination of chemotherapy and stem cell transplantation. Our case study reports a middle-aged African American woman with no other risk factors diagnosed with the acute form of adult T-cell leukemia-lymphoma and in remission after completing chemotherapy and a haploidentical stem cell transplantation.
摘要
由1型人类嗜T细胞病毒引起的成人T细胞白血病-淋巴瘤是一种罕见且侵袭性强的肿瘤，发病率和死亡率都很高。过去一直采用化疗进行治疗，但最近的研究表明，化疗与干细胞移植相结合可提高生存率。我们的病例研究报告了一名无其他风险因素的中年非裔美国女性，她被诊断患有急性成人T细胞白血病-淋巴瘤，在完成化疗和单倍体干细胞移植后病情缓解。
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