Ibuka N
Physiol Behav. 1987;39(3):321-6. doi: 10.1016/0031-9384(87)90229-0.
Circadian rhythms were examined in a congenitally anophthalmic rat mutant. All bilaterally anophthalmic rats had clear circadian rhythms in sleep-wakefulness as well as in locomotor activity, but the rhythms did not entrain to the light-dark (LD) cycle. However, two unilaterally anophthalmic rats, like sighted rats, reentrained their sleep-wakefulness rhythms to the LD cycle in 4 days after a 6 hr delaying phase-shift. The hypogenesis of the suprachiasmatic nuclei (SCN) that is correlated with absence of circadian activity rhythms in anophthalmic mice was not observed in these anophthalmic rats.
在一种先天性无眼大鼠突变体中对昼夜节律进行了研究。所有双侧无眼大鼠在睡眠-觉醒以及运动活动方面都有明显的昼夜节律，但这些节律并不与明暗（LD）周期同步。然而，两只单侧无眼大鼠，与有视力的大鼠一样，在6小时延迟相移后4天内其睡眠-觉醒节律重新与LD周期同步。在这些无眼大鼠中未观察到与无眼小鼠昼夜活动节律缺失相关的视交叉上核（SCN）发育不全。
