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Prevalence of Ipsilateral Nonstenotic Carotid Plaques on Computed Tomography Angiography in Embolic Stroke of Undetermined Source.不明来源栓塞性卒中患者计算机断层血管造影术同侧非狭窄性颈动脉斑块的患病率。
Stroke. 2020 Jun;51(6):1743-1749. doi: 10.1161/STROKEAHA.120.029404. Epub 2020 May 7.
2
Cryptogenic Stroke: Diagnostic Workup and Management.隐源性卒中:诊断检查与管理
Curr Treat Options Cardiovasc Med. 2019 Dec 3;21(11):77. doi: 10.1007/s11936-019-0786-4.
3
Multimodality Imaging in Carotid Web.颈动脉蹼的多模态成像
Front Neurol. 2019 Mar 12;10:220. doi: 10.3389/fneur.2019.00220. eCollection 2019.
4
A Systematic Literature Review of Patients With Carotid Web and Acute Ischemic Stroke.颈动脉壁血管外皮细胞瘤与急性缺血性脑卒中患者的系统性文献回顾
Stroke. 2018 Dec;49(12):2872-2876. doi: 10.1161/STROKEAHA.118.021907.
5
Multicenter Experience with Stenting for Symptomatic Carotid Web.症状性颈动脉嵴支架置入术的多中心经验
Interv Neurol. 2018 Oct;7(6):413-418. doi: 10.1159/000489710. Epub 2018 Jul 11.
6
Current Understanding and Gaps in Research of Carotid Webs in Ischemic Strokes: A Review.颈动脉梳在缺血性脑卒中中的研究现状及空白:综述
JAMA Neurol. 2019 Mar 1;76(3):355-361. doi: 10.1001/jamaneurol.2018.3366.
7
Carotid Webs: Radiographic Appearance and Significance.颈动脉膜:影像学表现及意义
Ochsner J. 2018 Summer;18(2):115-120. doi: 10.31486/toj.18.0001.
8
Prevalence of Carotid Web in Patients with Acute Intracranial Stroke Due to Intracranial Large Vessel Occlusion.颅内大动脉闭塞性急性颅内卒中患者的颈动脉窗患病率。
Radiology. 2018 Mar;286(3):1000-1007. doi: 10.1148/radiol.2017170094. Epub 2017 Oct 16.
9
Carotid Web (Intimal Fibromuscular Dysplasia) Has High Stroke Recurrence Risk and Is Amenable to Stenting.颈动脉嵴(内膜纤维肌发育不良)具有较高的卒中复发风险且适合进行支架置入术。
Stroke. 2017 Nov;48(11):3134-3137. doi: 10.1161/STROKEAHA.117.019020. Epub 2017 Oct 10.
10
Carotid Bulb Webs as a Cause of "Cryptogenic" Ischemic Stroke.颈动脉球部网作为“隐源性”缺血性卒中的一个病因
AJNR Am J Neuroradiol. 2017 Jul;38(7):1399-1404. doi: 10.3174/ajnr.A5208. Epub 2017 May 11.

网络浏览:颈动脉网的快速诊断与治疗

Web Browsing: High-Speed Diagnosis and Treatment of Carotid Artery Web.

作者信息

Schutt Charles DeMello, Pesquera Jorge J, Renati Swetha, Kaplan Daniel J, Mokin Maxim, Rose David Z

机构信息

Department of Neurology, University of South Florida Morsani College of Medicine, Tampa, FL,USA.

Department of Neuroscience, Health First Medical Group, Holmes Regional Medical Center, Melbourne, FL, USA.

出版信息

Neurohospitalist. 2022 Jul;12(3):498-503. doi: 10.1177/19418744221096650. Epub 2022 May 5.

DOI:10.1177/19418744221096650
PMID:35755224
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9214937/
Abstract

Although carotid artery web (CaW) was initially described in 1973 as a potential etiology of ischemic stroke, it still remains underrecognized. Because CaW is a membrane affixed perpendicularly from the carotid wall that projects out into the lumen above the bifurcation, it typically is not stenotic, and hence, utilizing only 1 vessel imaging modality during conventional stroke workup may instead lead to a diagnosis of ESUS: embolic stroke of undetermined source. The term ESUS was created in 2014 by researchers to define a subset of cryptogenic, nonlacunar (embolic-appearing) strokes without clear cardiac or vascular cause. In this review, we describe how, after multiple evaluations of vessels, CaW was diagnosed in relatively young patients (age 39-47 years old, without significant vascular risk factors) in whom otherwise were considered embolic stroke of undetermined source. This observation dovetails with the accompanying  article entitled, "Delayed Thrombus Formation on Carotid Web and Its Medical and Endovascular Management for Secondary Stroke Prevention." Not applicable. Case review. This report demonstrates the futility of antiplatelet therapy for a young patient with CaW-related stroke. Based on these collective experiences and review of the literature, we postulate that: (1) multiple vascular imaging modalities during stroke workup may result in a CaW diagnosis instead of ESUS; (2) young stroke patients without traditional vascular risk factors are candidates for this "web browsing" of extended imaging of vessels; and (3) carotid artery stenting (CAS) or carotid endarterectomy (CEA) may be preferred as first-line over medical therapy alone (ie, antiplatelet or anticoagulation) because CEA/CAS addresses the stroke etiology, CaW, definitively.

摘要

尽管颈动脉网(CaW)在1973年首次被描述为缺血性中风的一种潜在病因,但它仍然未得到充分认识。由于CaW是一种从颈动脉壁垂直附着并伸入分叉上方管腔的膜,它通常并不狭窄,因此,在传统的中风检查过程中仅使用一种血管成像方式可能反而会导致不明来源栓塞性卒中(ESUS)的诊断。ESUS这一术语是研究人员在2014年创造的,用于定义一组无明确心脏或血管病因的隐源性、非腔隙性(栓塞样)中风。在本综述中,我们描述了在对血管进行多次评估后,如何在相对年轻的患者(年龄39 - 47岁,无显著血管危险因素)中诊断出CaW,这些患者原本被认为是不明来源栓塞性卒中。这一观察结果与随附的题为《颈动脉网延迟血栓形成及其二级预防的药物和血管内治疗》的文章相吻合。不适用。病例回顾。本报告证明了抗血小板治疗对患有CaW相关中风的年轻患者无效。基于这些共同经验和文献回顾,我们推测:(1)中风检查过程中采用多种血管成像方式可能会诊断出CaW而非ESUS;(2)没有传统血管危险因素的年轻中风患者是这种对血管进行扩展成像的“网络浏览”的候选对象;(3)颈动脉支架置入术(CAS)或颈动脉内膜切除术(CEA)可能比单纯药物治疗(即抗血小板或抗凝治疗)更适合作为一线治疗,因为CEA/CAS能明确解决中风病因,即CaW。