Archana Archana, Sinha Asmita, Kokkayil Prathyusha, Pradhan Swetalina, Jha Sweta, Sarfraz Asim, Pati Binod K, Thakuria Bhaskar
Department of Microbiology, All India Institute of Medical Sciences, Patna, Phulwarisarif, Bihar, India.
Department of Dermatology, All India Institute of Medical Sciences, Patna, Phulwarisarif, Bihar, India.
IJID Reg. 2022 Mar 31;3:168-170. doi: 10.1016/j.ijregi.2022.03.023. eCollection 2022 Jun.
A 5-year-boy from Bihar, India was admitted to a tertiary care hospital with painful swelling over both lower limbs and buttocks, which had been increasing progressively for the past 1 year. The condition was initially undiagnosed and was later misdiagnosed as non-infective panniculitis, delaying treatment. Subsequently, the patient was diagnosed with subcutaneous entomophthoramycosis caused by spp. A preliminary diagnosis was made by considering the history, clinical features, radiological findings and histopathological examination of the biopsied tissue. The confirmatory diagnosis was made using conventional techniques on aspirated pus, which included KOH wet mount and fungal culture on Sabouraud dextrose agar tubes incubated at 28°C and 37°C, respectively. Lactophenol cotton blue mount and slide culture were performed for identification of the fungal isolate. The patient responded well to oral itraconazole and oral potassium iodide. Delayed diagnosis and extensive involvement in a rare case of subcutaneous entomophthoramycosis causing panniculitis emphasizes the importance of correct diagnosis and appropriate, effective treatment.
一名来自印度比哈尔邦的5岁男孩因双下肢及臀部疼痛性肿胀入住一家三级护理医院,这种肿胀在过去1年中逐渐加重。病情最初未被诊断出来,后来被误诊为非感染性脂膜炎,延误了治疗。随后,该患者被诊断为由 spp. 引起的皮下 Entomophthoramycosis(虫霉病)。通过考虑病史、临床特征、影像学检查结果以及活检组织的组织病理学检查做出了初步诊断。使用常规技术对吸出的脓液进行确诊,包括KOH湿片法以及分别在28°C和37°C培养的沙氏葡萄糖琼脂管上进行真菌培养。进行了石炭酸棉蓝封片和玻片培养以鉴定真菌分离株。患者对口服伊曲康唑和口服碘化钾反应良好。在一例罕见的导致脂膜炎的皮下 Entomophthoramycosis(虫霉病)中,诊断延迟和广泛受累强调了正确诊断以及恰当、有效治疗的重要性。