Yociss Megan, Fei Baowei
The University of Texas at Dallas, Department of Bioengineering, Richardson, TX.
The University of Texas Southwestern Medical Center, Department of Radiology, Dallas, TX.
Proc SPIE Int Soc Opt Eng. 2021 Feb;11602. doi: 10.1117/12.2581962. Epub 2021 Feb 24.
The intensity of backscattered ultrasound signal from heart muscle is known to be related to the angle between cardiac fibers and the insonification direction. In this work, a GPU-based method of simulating three-dimensional (3D) echocardiographic images from an empirically derived angle-to-backscatter relationship is developed and validated. Images of a rotating fiber phantom are simulated, and it is validated that the angle-to-backscatter relationship is accurately reflected by the simulated envelope data. In a second experiment, echocardiography images are simulated from a diffusion tensor magnetic resonance imaging (DT-MRI) volume of a canine heart to demonstrate that the method produces view-dependent speckle. 3D volumes of a parametrically generated ideal left ventricle phantom are also simulated and processed into fiber orientation maps using the underlying quantitative parameters. Images are simulated based on the characteristics of a 35-by-32 two-dimensional (2D) matrix array probe and a clinical one-dimensional (1D) phased array probe. The processed fiber volumes exhibit good agreement with the virtual phantom's ground truth, having an average acute angle error (AAE) of less than 10 degrees for both probes. The simulation method is fast and opens a new approach for ultrasound fiber imaging.
已知来自心肌的背向散射超声信号强度与心肌纤维和超声入射方向之间的夹角有关。在这项工作中，开发并验证了一种基于图形处理器（GPU）的方法，该方法可根据经验得出的角度与背向散射关系模拟三维（3D）超声心动图图像。模拟了旋转纤维模型的图像，并验证了模拟包络数据能准确反映角度与背向散射的关系。在第二个实验中，从犬心脏的扩散张量磁共振成像（DT-MRI）容积模拟超声心动图图像，以证明该方法产生了与视角相关的散斑。还模拟了参数生成的理想左心室模型的3D容积，并使用基础定量参数将其处理为纤维取向图。基于35×32二维（2D）矩阵阵列探头和临床一维（1D）相控阵探头的特性模拟图像。处理后的纤维容积与虚拟模型的真实情况具有良好的一致性，两种探头的平均锐角误差（AAE）均小于10度。该模拟方法速度快，为超声纤维成像开辟了一条新途径。
