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脾梗死作为原发性血小板增多症的首发表现

Splenic Infarct as the Presenting Manifestation of Essential Thrombocythemia.

作者信息

Khade Shalaka, Khera Sudeep, Varshney Vaibhav Kumar, Sharma Deepak Kumar, Nayar Raghav, Purohit Abhishek

机构信息

Department of Pathology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.

Department of Surgical Gastroenterology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.

出版信息

Ochsner J. 2022 Summer;22(2):188-191. doi: 10.31486/toj.21.0073.

Abstract

Essential thrombocythemia is a chronic myeloproliferative neoplasm characterized by thrombotic and hemorrhagic complications. Essential thrombocythemia can be considered a risk factor for thrombotic events. A 34-year-old female presented with sudden onset of abdominal pain from splenic infarction for which she underwent splenectomy. Bone marrow examination performed because of increasing thrombocytosis led to a diagnosis of essential thrombocythemia. Postoperatively, she was maintained on low-dose aspirin and doing well at follow-up. Our patient had an undiagnosed case of essential thrombocythemia and presented with symptoms related to splenic infarction. To the best of our knowledge, few cases of splenic infarction consequent to essential thrombocythemia have been reported.

摘要

原发性血小板增多症是一种慢性骨髓增殖性肿瘤,其特征为血栓形成和出血并发症。原发性血小板增多症可被视为血栓形成事件的一个危险因素。一名34岁女性因脾梗死突发腹痛就诊,为此接受了脾切除术。由于血小板增多症加重而进行的骨髓检查确诊为原发性血小板增多症。术后,她一直服用小剂量阿司匹林,随访情况良好。我们的患者患有一例未被诊断出的原发性血小板增多症,并出现了与脾梗死相关的症状。据我们所知,很少有原发性血小板增多症导致脾梗死的病例报道。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d379/9196959/22bb0400633d/toj-21-0073-figure1.jpg

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