Sayyahmelli Sara, Sayyahmelli Sima, Salamat Shahriar, Başkaya Mustafa K
Department of Neurological Surgery, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin, United States.
Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States.
J Neurol Surg Rep. 2022 Jun 24;83(2):e63-e66. doi: 10.1055/a-1858-7483. eCollection 2022 Apr.
Epidermoid tumors (ET) are slow-growing masses where malignant transformations occur extremely rarely. Malignant transformation warning signs are the rapid-onset, progression, and recurrence of symptoms. The radiologic evidence for malignant transformation is contrast enhancement with rapid growth, observed with magnetic resonance imaging (MRI) or computed tomography scans. Here, we provide a case report of a 68-year-old woman with a long-standing history of left-sided cerebellopontine angle ET who presented with a recent worsening of symptoms, and MRI observation of new ET contrast enhancement. Surgical re-exploration and histopathologic confirmation are mandatory in this setting of recent symptom worsening and MRI observation of rapid mass growth.
表皮样肿瘤（ET）是生长缓慢的肿块，极少发生恶性转化。恶性转化的警示信号是症状的快速出现、进展和复发。恶性转化的影像学证据是在磁共振成像（MRI）或计算机断层扫描中观察到的伴有快速生长的对比增强。在此，我们报告一例68岁女性病例，该患者有长期左侧桥小脑角ET病史，近期症状加重，MRI观察到新的ET对比增强。在近期症状恶化且MRI观察到肿块快速生长的情况下，必须进行手术再次探查和组织病理学确诊。
