Izudi Jonathan, Tamwesigire Imelda K, Bajunirwe Francis
Department of Community Health, Mbarara University of Science and Technology, Mbarara, Uganda.
Infectious Diseases Institute, Makerere University, Kampala, Uganda.
IJID Reg. 2022 Jan 6;2:107-109. doi: 10.1016/j.ijregi.2022.01.001. eCollection 2022 Mar.
Inaccurate reporting of tuberculosis (TB) data to the district and national TB control programmes undermines effective TB control, yet this remains understudied. This study assessed the accuracy of the paper-based approach compared with the World Health Organization (WHO) standard TB treatment outcome as the gold standard for the determination of TB treatment outcome. Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of the paper-based approach, as well as the percentage agreement between the paper-based approach and the WHO standard TB treatment outcome, are reported. Data from 987 participants were used. Ninety-three participants were misclassified as cured and 195 were misclassified as not cured by the paper-based approach, giving 62.7% sensitivity, 80.0% specificity, 77.9% PPV, 65.5% NPV and percentage agreement of 70.8%. Treatment failure had 64.7% sensitivity, 99.9% specificity, 52.4% PPV, 99.4% NPV, and percentage agreement of 98.4%. Treatment success had 98.8% sensitivity, 96.8% specificity, 99.2% PPV and 94.8% NPV. The paper-based approach was found to report treatment success accurately, but did not report cure and treatment failure accurately. Interventions are thus required to improve the accuracy of the paper-based approach.
向地区和国家结核病控制项目不准确地报告结核病数据会破坏有效的结核病控制，但这一点仍未得到充分研究。本研究将纸质记录方法的准确性与世界卫生组织（WHO）标准结核病治疗结果进行比较，将后者作为确定结核病治疗结果的金标准进行评估。报告了纸质记录方法的灵敏度、特异度、阳性预测值（PPV）和阴性预测值（NPV），以及纸质记录方法与WHO标准结核病治疗结果之间的一致性百分比。使用了来自987名参与者的数据。通过纸质记录方法，有93名参与者被误分类为治愈，195名被误分类为未治愈，灵敏度为62.7%，特异度为80.0%，PPV为77.9%，NPV为65.5%，一致性百分比为70.8%。治疗失败的灵敏度为64.7%，特异度为99.9%，PPV为52.4%，NPV为99.4%，一致性百分比为98.4%。治疗成功的灵敏度为98.8%，特异度为96.8%，PPV为99.2%，NPV为94.8%。发现纸质记录方法能准确报告治疗成功情况，但不能准确报告治愈和治疗失败情况。因此需要采取干预措施来提高纸质记录方法的准确性。
