• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

酷似急性冠状动脉综合征的壁内食管血肿:机械心脏瓣膜置换术后华法林治疗的并发症

Intramural Esophageal Hematoma Mimicking Acute Coronary Syndrome: Complication of Warfarin Use in a Mechanical Heart Valve Patient.

作者信息

Alirezaei Toktam, Irilouzadian Rana, Pirsalehi Ali, Nekooghadam Sayyed Mojtaba

机构信息

Cardiology Department of Shohadaye-Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

Case Rep Med. 2022 Jun 15;2022:5636989. doi: 10.1155/2022/5636989. eCollection 2022.

DOI:10.1155/2022/5636989
PMID:35757464
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9217597/
Abstract

A 59-year-old female with a history of mitral valve replacement presented to emergency department, complaining of sudden-onset retrosternal chest pain since 4 hours ago. Electrocardiogram, laboratory tests, and computed tomography (CT) angiography of aorta were performed and ruled out aortic dissection and cardiovascular events. However, new complaint of odynophagia, dysphagia, and incidental findings in CT angiography proposed esophageal pathologies. After initial workup including upper gastrointestinal endoscopy, intramural esophageal hematoma was diagnosed. Laboratory tests revealed significant reduction in the hemoglobin level. Management of warfarin-induced major bleeding in a patient whom anticoagulation was necessary for the prevention of mechanical heart valve thrombosis was challenging. The patient recovered fully with conservative treatment and was discharged on hospital day 14 with low molecular weight heparin. We described a case of intramural esophageal hematoma as a rare condition that could be misdiagnosed as a cardiovascular emergent disease and would be worsened by antiplatelet and anticoagulation therapy. Accordingly, it is important to differentiate intramural esophageal hematoma from cardiac ischemic events. Another challenge was correction of coagulation in the presence of mechanical mitral valve. Fortunately, we had a favorable outcome following conservative management.

摘要

一名有二尖瓣置换病史的59岁女性因4小时前突发胸骨后胸痛就诊于急诊科。进行了心电图、实验室检查及主动脉计算机断层扫描(CT)血管造影,排除了主动脉夹层和心血管事件。然而,新出现的吞咽疼痛、吞咽困难主诉以及CT血管造影中的偶然发现提示存在食管病变。经过包括上消化道内镜检查在内的初步检查,诊断为壁内食管血肿。实验室检查显示血红蛋白水平显著降低。对于一名为预防机械性心脏瓣膜血栓形成而必须进行抗凝治疗的患者,处理华法林引起的严重出血具有挑战性。患者经保守治疗完全康复,于住院第14天出院,出院时使用低分子量肝素。我们描述了一例壁内食管血肿病例,这是一种罕见疾病,可能被误诊为心血管急症,且抗血小板和抗凝治疗会使其病情恶化。因此,将壁内食管血肿与心脏缺血事件相鉴别很重要。另一个挑战是在存在机械二尖瓣的情况下纠正凝血功能。幸运的是,经过保守治疗我们取得了良好的结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fe1/9217597/578a0e62cc6b/CRIM2022-5636989.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fe1/9217597/f45e7745edfd/CRIM2022-5636989.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fe1/9217597/700cd7e55eec/CRIM2022-5636989.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fe1/9217597/f02429684cae/CRIM2022-5636989.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fe1/9217597/578a0e62cc6b/CRIM2022-5636989.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fe1/9217597/f45e7745edfd/CRIM2022-5636989.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fe1/9217597/700cd7e55eec/CRIM2022-5636989.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fe1/9217597/f02429684cae/CRIM2022-5636989.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fe1/9217597/578a0e62cc6b/CRIM2022-5636989.004.jpg

相似文献

1
Intramural Esophageal Hematoma Mimicking Acute Coronary Syndrome: Complication of Warfarin Use in a Mechanical Heart Valve Patient.酷似急性冠状动脉综合征的壁内食管血肿:机械心脏瓣膜置换术后华法林治疗的并发症
Case Rep Med. 2022 Jun 15;2022:5636989. doi: 10.1155/2022/5636989. eCollection 2022.
2
[A Case of Intramural Hematoma of the Esophagus Mimicking Acute Coronary Syndrome].[一例酷似急性冠状动脉综合征的食管壁内血肿病例]
Korean J Gastroenterol. 2017 Apr 25;69(4):239-242. doi: 10.4166/kjg.2017.69.4.239.
3
Intramural Esophageal Dissection: A Rare Cause of Acute Chest Pain after Percutaneous Coronary Intervention.壁内食管夹层:经皮冠状动脉介入治疗后急性胸痛的罕见原因。
J Tehran Heart Cent. 2019 Jul;14(3):138-140.
4
Spontaneous intramural esophageal hematoma (IEH) secondary to anticoagulation and/or thrombolysis therapy in the setting of a pulmonary embolism: a case report.肺栓塞背景下抗凝和/或溶栓治疗继发的自发性食管壁内血肿(IEH):一例报告
J Radiol Case Rep. 2013 Feb 1;7(2):1-10. doi: 10.3941/jrcr.v7i2.1210. Print 2013 Feb.
5
Intramural Hematoma of the Esophagus Complicating Severe Preeclampsia.食管壁内血肿并发重度子痫前期
Case Rep Obstet Gynecol. 2017;2017:6304194. doi: 10.1155/2017/6304194. Epub 2017 May 18.
6
Nasogastric Tubes Can Cause Intramural Hematoma of the Esophagus.鼻胃管可导致食管壁内血肿。
Am J Case Rep. 2019 Feb 20;20:224-227. doi: 10.12659/AJCR.914133.
7
Case Report: Large ileal intramural hematoma presenting as an intestinal obstruction in a patient on Warfarin with incidental breast cancer.病例报告:一名服用华法林且患有偶发性乳腺癌的患者出现大的回肠壁内血肿并表现为肠梗阻。
F1000Res. 2018 Jun 11;7:724. doi: 10.12688/f1000research.14848.2. eCollection 2018.
8
Anticoagulant management of pregnant women with mechanical heart valve replacement during perioperative period.围手术期机械心脏瓣膜置换术后孕妇的抗凝管理
Arch Gynecol Obstet. 2016 Jan;293(1):69-74. doi: 10.1007/s00404-015-3768-0. Epub 2015 Jun 6.
9
Aortic intramural hematoma and hepatic artery pseudoaneurysm: unusual complication following resuscitation.主动脉壁内血肿和肝动脉假性动脉瘤:复苏后罕见的并发症。
Am J Emerg Med. 2014 Jan;32(1):107.e1-4. doi: 10.1016/j.ajem.2013.08.012. Epub 2013 Sep 21.
10
Massive intramural esophageal hematoma secondary to anticoagulation therapy for mitral valve replacement.二尖瓣置换术后抗凝治疗继发的巨大食管壁内血肿。
J Card Surg. 2016 Dec;31(12):740-741. doi: 10.1111/jocs.12864. Epub 2016 Nov 1.

引用本文的文献

1
Large Esophageal Intramural Hematoma After Solid Food Ingestion in a Patient Without Identifiable Inherited or Acquired Coagulopathy.一名无明确遗传性或获得性凝血功能障碍的患者在摄入固体食物后出现巨大食管壁内血肿。
ACG Case Rep J. 2023 Jun 8;10(6):e01067. doi: 10.14309/crj.0000000000001067. eCollection 2023 Jun.

本文引用的文献

1
Intramural Esophageal Hematoma Secondary to Food Ingestion.食物摄入继发的壁内食管血肿
Cureus. 2019 Sep 11;11(9):e5623. doi: 10.7759/cureus.5623.
2
Spontaneous Intramural Esophageal Hematoma.
Clin Gastroenterol Hepatol. 2018 Feb;16(2):e19-e20. doi: 10.1016/j.cgh.2017.04.027. Epub 2017 Apr 23.
3
Spontaneous intramural esophageal hematoma (IEH) secondary to anticoagulation and/or thrombolysis therapy in the setting of a pulmonary embolism: a case report.肺栓塞背景下抗凝和/或溶栓治疗继发的自发性食管壁内血肿(IEH):一例报告
J Radiol Case Rep. 2013 Feb 1;7(2):1-10. doi: 10.3941/jrcr.v7i2.1210. Print 2013 Feb.
4
Spontaneous intramural esophageal hematoma: case report and review.自发性食管壁内血肿:病例报告与文献复习
Can J Gastroenterol. 2006 Apr;20(4):285-6. doi: 10.1155/2006/764714.
5
Spontaneous intramural rupture of the esophagus: clinical presentation and endoscopic findings.
Gastrointest Endosc. 2002 Jul;56(1):134-6. doi: 10.1067/mge.2002.125360.
6
Extensive spontaneous submucosal dissection of the esophagus: long-term sequential endoscopic observation and treatment.
Gastrointest Endosc. 2002 Feb;55(2):262-5. doi: 10.1067/mge.2002.121872.
7
A case of intramural esophageal hematoma: complication of anticoagulation with heparin.1例食管壁内血肿:肝素抗凝治疗的并发症。
Gastrointest Endosc. 2000 Oct;52(4):559-61. doi: 10.1067/mge.2000.108664.
8
Intramural esophageal hematoma: a diagnostic dilemma.
Gastrointest Endosc. 2000 Jun;51(6):757-9. doi: 10.1067/mge.2000.104350.
9
Dissecting intramural haematoma of the oesophagus exacerbated by heparin therapy.
QJM. 1999 Feb;92(2):123-4. doi: 10.1093/qjmed/92.2.123.
10
Spontaneous oesophageal haematoma presenting as acute myocardial infarction: implications for thrombolytic therapy.表现为急性心肌梗死的自发性食管血肿:对溶栓治疗的影响
Postgrad Med J. 1991 Aug;67(790):779-80. doi: 10.1136/pgmj.67.790.779.