Gerald Arincheyan, McCandless Max, Sheth Avani, Aihara Hiroyuki, Russo Sheila
Department of Mechanical Engineering, Boston University, Boston, MA 02215, USA.
Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA.
Adv Intell Syst. 2022 Apr;4(4). doi: 10.1002/aisy.202100254. Epub 2022 Feb 20.
Colonoscopies allow surgeons to detect common diseases i.e. colorectal cancer, ulcers and other ailments. However, there is a risk of bleeding in the lower gastrointestinal (GI) tract while maneuvering endoscopes. This may be due to perforations, hemorrhaging, polyps, diverticuli or post-biopsy complications. Thus, it is essential for the surgeon to be able to detect bleeding at the site and evaluate the severity of blood leakage. This paper presents a soft sensor that can detect the presence of blood at the bleeding site during colonoscopies. The sensor consists of optical waveguides that interface with a microfluidic channel. Blood flow causes absorption and scattering of incident light that can be picked up by the optical sensing apparatus via light transmission through the waveguide. The surgeon can be alerted when bleeding occurs through a graphical user interface. The device is compact and measures only 1 mm thick. This allows the sensor to be circumferentially mounted onto a colonoscope at different locations. The sensor is able to record the presence of blood as an optical loss, rapidly detect the presence of blood in under 100 milliseconds as it enters the microchannel, and differentiate between gastric fluid and blood through changes in measured optical loss.
结肠镜检查可让外科医生检测常见疾病,即结直肠癌、溃疡和其他疾病。然而,在内窥镜操作过程中,下消化道存在出血风险。这可能是由于穿孔、出血、息肉、憩室或活检后并发症引起的。因此,外科医生能够在出血部位检测到出血并评估漏血的严重程度至关重要。本文介绍了一种软传感器,它可以在结肠镜检查期间检测出血部位是否存在血液。该传感器由与微流体通道相连的光波导组成。血流会导致入射光的吸收和散射,光学传感设备可通过光波导中的光传输来检测到这种吸收和散射。当出血发生时,外科医生可通过图形用户界面收到警报。该设备体积小巧,厚度仅为1毫米。这使得传感器能够在不同位置沿圆周方向安装到结肠镜上。该传感器能够将血液的存在记录为光损失,在血液进入微通道后不到100毫秒内快速检测到血液的存在,并通过测量光损失的变化区分胃液和血液。