• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[Effects of Logacer in patients with chronic brain ischemia and moderate cognitive impairment: results of non-interventional clinical observation].

作者信息

Zakharov V V

机构信息

Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.

出版信息

Zh Nevrol Psikhiatr Im S S Korsakova. 2022;122(6):93-99. doi: 10.17116/jnevro202212206193.

DOI:10.17116/jnevro202212206193
PMID:35758953
Abstract

OBJECTIVE

To assess the degree of satisfaction of outpatient neurologists with the results of therapy with Logacer 4 ml/1000 mg IM once daily in patients with chronic cerebral ischemia (CCI) and moderate cognitive impairment (MCI) in routine clinical practice.

MATERIAL AND METHODS

The study involved 7777 patients with chronic cerebral ischemia aged 55-75 years. All patients had moderate cognitive impairment according to the MMSE scale. The patients were prescribed injection therapy with Logacer 4 ml/1000 mg 1 r/day IM for 10 days. Patient satisfaction and adherence to therapy was assessed using the Likert scale.

RESULTS

At the indicated doses, Logacer caused a pronounced positive effect on the neurological status and cognitive functions of patients with CCI and MCI. 3733 (49%) patients rated their satisfaction with the therapy with Logacer 3323 (43%) as 5 points - 4 points. 3988 (52%) patients rated adherence to therapy with Logacer at 5 points, 3261 (43%) patients - at 4 points.

CONCLUSION

The drug Logacer is characterized by high effectiveness and good tolerability in patients with CCI.

摘要

相似文献

1
[Effects of Logacer in patients with chronic brain ischemia and moderate cognitive impairment: results of non-interventional clinical observation].
Zh Nevrol Psikhiatr Im S S Korsakova. 2022;122(6):93-99. doi: 10.17116/jnevro202212206193.
2
[Observational study of the efficacy and safety of the drug Ampasse in patients with moderate cognitive impairment in chronic cerebral ischemia].
Zh Nevrol Psikhiatr Im S S Korsakova. 2023;123(10):75-80. doi: 10.17116/jnevro202312310175.
3
[Neurometabolic therapy of mild cognitive impairment in patients with chronic cerebral ischemia].[慢性脑缺血患者轻度认知障碍的神经代谢治疗]
Zh Nevrol Psikhiatr Im S S Korsakova. 2024;124(3):42-51. doi: 10.17116/jnevro202412403142.
4
[Efficacy and safety of the drug Cellex for the treatment of patients with cognitive impairment with chronic cerebral ischemia - results of a multicenter randomized double-blind placebo-controlled clinical trial].[药物Cellex治疗慢性脑缺血性认知障碍患者的疗效与安全性——一项多中心随机双盲安慰剂对照临床试验的结果]
Zh Nevrol Psikhiatr Im S S Korsakova. 2023;123(5):108-116. doi: 10.17116/jnevro2023123051108.
5
[The assessment of the efficacy of Ethoxidol treatment in patients with chronic cerebral ischemia].[乙氧醇治疗慢性脑缺血患者的疗效评估]
Zh Nevrol Psikhiatr Im S S Korsakova. 2021;121(9):31-37. doi: 10.17116/jnevro202112109131.
6
[Clinical efficacy and safety of Picamilon in patients with progressive chronic cerebral ischemia].
Zh Nevrol Psikhiatr Im S S Korsakova. 2024;124(8):71-80. doi: 10.17116/jnevro202412408171.
7
[The use of cereton in patients with chronic brain ischemia and moderate cognitive impairment].[塞雷通在慢性脑缺血和中度认知障碍患者中的应用]
Zh Nevrol Psikhiatr Im S S Korsakova. 2014;114(12):78-83. doi: 10.17116/jnevro201411412178-83.
8
[Results of a multicenter observational program to evaluate the effectiveness of complex therapy of patients with chronic cerebrovascular pathology with cognitive impairment with Cortexin and Neuromexol (CORNELia study)].[一项多中心观察性项目的结果,该项目旨在评估使用Cortexin和Neuromexol(CORNELia研究)对患有慢性脑血管病变并伴有认知障碍的患者进行综合治疗的有效性]
Zh Nevrol Psikhiatr Im S S Korsakova. 2023;123(12):34-41. doi: 10.17116/jnevro202312312134.
9
[Integrative assessment of the effectiveness and safety of outpatient use of Picamilon].
Zh Nevrol Psikhiatr Im S S Korsakova. 2024;124(7):119-130. doi: 10.17116/jnevro2024124071119.
10
[The efficacy of cortexin and memantinol (memantine) in the treatment of cognitive impairment in patients with chronic cerebral ischemia].[皮质激素与美金刚(盐酸美金刚)治疗慢性脑缺血患者认知障碍的疗效]
Zh Nevrol Psikhiatr Im S S Korsakova. 2018;118(1):30-36. doi: 10.17116/jnevro20181181130-36.