牙龈鳞状细胞癌 1 例：诊断挑战。
A rare case of squamous cell carcinoma of the gingiva: A diagnostic challenge.
机构信息
Oral Semiology and Oral Pathology, Department of Oral Diagnosis, Piracicaba School of Dentistry, University of Campinas, Piracicaba, São Paulo, Brazil.
Oral Semiology and Oral Pathology, Department of Oral Diagnosis, Piracicaba School of Dentistry, University of Campinas, Piracicaba, São Paulo, Brazil.
出版信息
Oral Oncol. 2022 Sep;132:105995. doi: 10.1016/j.oraloncology.2022.105995. Epub 2022 Jun 24.
BACKGROUND
Oral squamous cell carcinoma (OSCC) of the gingiva represents less than 6% of intraoral carcinomas.
CASE REPORT
A 51-year-old male patient presented with a history of a symptomatic red spot with periods of remission and recurrence in the mandibular gingiva. On clinical examination red and white areas were observed in the gingiva, particularly around the left lower molars. Diagnosis of gingival lichen planus was suspected and topical corticosteroids was prescribed. A good clinical response was observed with reduction of symptom. The patient remained in regular follow-up and after 9 months, the lesion suddenly changed, became ulcerated and diagnosis of OSCC was established.
CONCLUSION
The clinical manifestation of OSCC can eventually mimic other even more common lesions of the oral mucosa, highlighting the importance of considering OSCC as differential diagnosis of any unexplained and persistent lesion in the oral cavity.
背景
牙龈口腔鳞状细胞癌（OSCC）占口腔内癌的比例不足 6%。
病例报告
一名 51 岁男性患者，下颌牙龈有一处红斑，有症状且反复发作，时好时坏。临床检查时发现牙龈有红白相间的区域，尤其是左下磨牙周围。怀疑是牙龈扁平苔藓，给予局部皮质类固醇治疗。症状明显减轻，临床反应良好。患者定期随访，9 个月后，病变突然改变，出现溃疡，诊断为 OSCC。
结论
OSCC 的临床表现最终可能类似于口腔黏膜的其他更常见的病变，这凸显了将 OSCC 作为任何不明原因和持续存在的口腔内病变的鉴别诊断的重要性。
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