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犬齿密螺旋体引起的类白血病反应患者合并异型Pelger-Huët 异常败血性休克。

Septic shock caused by Capnocytophaga canimorsus in a patient with heterozygous Pelger-Huët anomaly.

机构信息

Intensive Care Unit. University Son Llàtzer Hospital, Ctra. Manacor PK 4 (Son Ferriol), 07198, Palma, Spain.

Hematology Service. University Son Llàtzer Hospital, Palma, Spain.

出版信息

Int J Hematol. 2022 Nov;116(5):807-811. doi: 10.1007/s12185-022-03400-1. Epub 2022 Jun 27.

Abstract

Capnocytophaga canimorsus is a Gram-negative bacillus of the commensal flora of dogs and cats that can cause infections in humans through bites, scratches or contact with oral secretions. It can be difficult to identify in clinical microbiology laboratories because of the need for specific culture media. We present the case of a patient with no relevant medical history who was admitted with septic shock, where blood smear examination was crucial for the etiologic diagnosis of Capnocytophaga canimorsus infection. The patient was also diagnosed Pelger-Huët anomaly, a condition causing a defect in neutrophil chemotaxis, which may have contributed to the severity of the infection.

摘要

贪噬细胞菌是一种革兰氏阴性杆菌,是犬、猫共生菌群的一部分,可通过咬伤、抓伤或接触口腔分泌物使人类感染。由于需要特定的培养基,这种细菌在临床微生物学实验室中很难被识别。我们报告了一例无相关病史的患者,因感染性休克入院,血涂片检查对贪噬细胞菌感染的病因诊断至关重要。该患者还被诊断为Pelger-Huët 异常,这是一种导致中性粒细胞趋化性缺陷的病症,这可能导致了感染的严重程度。

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