Wang Jili, Qu Shanshan, Xu Qinyan, Jin Zhaofeng, Li Tian, Zhang Shuxian, Sun Xihe
Department of Medical Imaging, Weifang Medical University, Weifang 261653, China.
Imaging Department, Shouguang People's Hospital, Shouguang 262700, China.
J Oncol. 2022 Jun 18;2022:2738892. doi: 10.1155/2022/2738892. eCollection 2022.
The aim of this study is to investigate gadolinium-diethylenetriaminepentacetate (Gd-DTPA) retention in the cystic area of brain metastasis and its correlation with MRI signs.
Clinical and MRI data of 76 patients with brain metastasis in the cystic area were collected. The contrast signal intensity (CSI) of the cystic area and edema area in the plain scan, enhanced scan, and plain scan after enhancement within 1 month (hereafter referred to as "enhanced plain scan") were analyzed to determine whether Gd-DTPA was retained in these areas. The lesions with higher CSI values on the enhanced plain scan were classified as the Gd-DTPA retention group and the remaining lesions as the Gd-DTPA-free group. The two groups were compared to determine significant differences in primary lesion type, tumor size, tumor location, capsule wall thickness and morphology, peritumoral edema, and renal function.
A total of 123 lesions were detected. The CSI of the enhanced plain scan exceeded that of the plain scan and enhanced scan in the cystic area ( < 0.05). There were 54 lesions (43.9%) with Gd-DTPA retention in the cystic area and 69 lesions (56.1%) without Gd-DTPA retention. Significant differences were observed in tumor size and cystic wall thickness between the two groups ( < 0.05), while no significant differences in primary lesion type, cystic wall shape, peritumoral edema, or function were observed.
The retention of Gd-DTPA was found in the cystic area of some brain metastases, which was correlated with tumor size and cystic wall thickness.
本研究旨在探讨钆喷酸葡胺（Gd-DTPA）在脑转移瘤囊性区域的潴留情况及其与MRI征象的相关性。
收集76例脑转移瘤囊性区域患者的临床及MRI资料。分析平扫、增强扫描及增强后1个月内平扫（以下简称“增强平扫”）时囊性区域及水肿区域的对比剂信号强度（CSI），以确定Gd-DTPA是否在这些区域潴留。增强平扫时CSI值较高的病变归为Gd-DTPA潴留组，其余病变归为无Gd-DTPA潴留组。比较两组在原发灶类型、肿瘤大小、肿瘤位置、囊壁厚度及形态、瘤周水肿和肾功能方面的差异。
共检测到123个病变。增强平扫时囊性区域的CSI高于平扫及增强扫描（<0.05）。囊性区域有54个病变（43.9%）存在Gd-DTPA潴留，69个病变（56.1%）无Gd-DTPA潴留。两组在肿瘤大小和囊壁厚度方面存在显著差异（<0.05），而在原发灶类型、囊壁形状、瘤周水肿或功能方面未观察到显著差异。
部分脑转移瘤的囊性区域存在Gd-DTPA潴留，其与肿瘤大小和囊壁厚度相关。
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