Department of Psychiatry and Psychotherapy, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.
Department of Psychiatry and Psychotherapy, Carl Gustav Carus University Hospital, Medical Faculty, Technische Universität, Dresden, Germany.
Eur Psychiatry. 2022 Jun 28;65(1):e41. doi: 10.1192/j.eurpsy.2022.33.
Mental illness is known to come along with a large mortality gap compared to thegeneral population and it is a risk for COVID-19 related morbidity andmortality. Achieving high vaccination rates in people with mental illness is therefore important. Reports are conflicting on whether vaccination rates comparable to those of the general population can be achieved and which variables represent risk factors for nonvaccination in people with mental illness.
The COVID Ψ Vac study collected routine data on vaccination status, diagnostic groups, sociodemographics, and setting characteristics from in- and day-clinic patients of 10 psychiatric hospitals in Germany in August 2021. Logistic regression modeling was used to determine risk factors for nonvaccination.
Complete vaccination rates were 59% ( = 776) for the hospitalized patients with mental illness versus 64% for the regionally and age-matched general population. Partial vaccination rates were 68% ( = 893) for the hospitalised patients with mental illness versus 67% for the respective general population and six percentage ( = 74) of this hospitalized population were vaccinated during the hospital stay. Rates showed a large variation between hospital sites. An ICD-10 group F1, F2, or F4 main diagnosis, younger age, and coercive accommodation were further risk factors for nonvaccination in the model.
Vaccination rates were lower in hospitalized people with mental illness than in the general population. By targeting at-risk groups with low-threshold vaccination programs in all health institutions they get in contact with, vaccination rates comparable to those in the general population can be achieved.
与普通人群相比，精神疾病已知存在较大的死亡率差距，并且是与 COVID-19 相关发病率和死亡率的风险因素。因此，在精神疾病患者中实现高疫苗接种率非常重要。关于能否达到与普通人群相当的疫苗接种率以及哪些变量代表精神疾病患者未接种疫苗的风险因素，报告结果存在矛盾。
COVID Ψ Vac 研究于 2021 年 8 月从德国 10 家精神病院的住院和日间门诊患者中收集了疫苗接种状况、诊断组、社会人口统计学和环境特征的常规数据。使用逻辑回归模型确定未接种疫苗的风险因素。
患有精神疾病的住院患者完全接种疫苗的比例为 59%（=776），而该地区和年龄匹配的普通人群的比例为 64%。患有精神疾病的住院患者部分接种疫苗的比例为 68%（=893），而相应的普通人群的比例为 67%，该住院人群中有 6%（=74）在住院期间接种了疫苗。各医院之间的接种率存在很大差异。ICD-10 组 F1、F2 或 F4 主要诊断、年龄较小和强制性住院是模型中未接种疫苗的进一步风险因素。
与普通人群相比，住院精神疾病患者的疫苗接种率较低。通过在所有接触的卫生机构中针对高风险人群开展低门槛疫苗接种计划，可以实现与普通人群相当的疫苗接种率。
