School of Public Health, College of Medicine and Health Sciences, Wachemo University, Hosaena, Ethiopia.
Department of Epidemiology and Biostatistics, School of Public Health, College of Medicine and Health Sciences, Mizan-Tepi University, Mizan Aman, Ethiopia.
Womens Health (Lond). 2022 Jan-Dec;18:17455057221109222. doi: 10.1177/17455057221109222.
Implanon discontinuation before the recommended time is problematic, as it puts women at risk of unwanted pregnancies and unsafe abortions, along with negative maternal health outcomes. Although the magnitude and determinants of Implanon discontinuation have been studied in Ethiopia, the results were inconsistent, with significant variability. Hence, this systematic review and meta-analysis aimed at estimating the pooled prevalence of Implanon discontinuation and its determinants in Ethiopia.
A comprehensive search of studies published before 18 February 2022 was done using electronic databases such as PubMed, Embase, Google Scholar, Scopus, Web of Science, Science Direct, and Cochrane Library. The relevant data were extracted using a Microsoft Excel 2013 and analyzed using STATA Version 16. A random-effect meta-analysis model was used to compute pooled prevalence and odds ratio. The Cochrane test statistics and tests were used to assess the heterogeneity of the included studies. A funnel plot, Begg's, and Egger's tests were used to check for the presence of publication bias.
A total of 11 studies with 4320 study participants were included in this meta-analysis. The overall pooled prevalence of Implanon discontinuation in Ethiopia was found to be 32.62% (95% confidence interval = 24.10, 41.13). There was significant heterogeneity among the included studies ( = 97.4%, < 0.001). However, there was no statistical evidence of publication bias ( = 0.533). Dissatisfied with service provision at the time of insertion (odds ratio = 3.92, 95% confidence interval = 1.54, 6.29), not having pre-insertion counseling (odds ratio = 2.98, 95% confidence interval = 1.91, 5.04), the absence of post-insertion follow-up (odds ratio = 4.03, 95% confidence interval = 2.17, 5.90), and the presence of side effects (odds ratio = 2.93, 95% confidence interval = 1.87, 3.98) were found to be determinants of Implanon discontinuation.
According to this systematic review and meta-analysis, one-third of Ethiopian women discontinued Implanon before the recommended time (3 years). Program managers and service providers should consider using more evidence-based and participatory counseling approaches to enhance client satisfaction. Furthermore, family planning service delivery points should be equipped to manage and reassure women who are experiencing side effects.
在推荐时间之前停止使用 Implanon 会带来问题,因为这会使妇女面临意外怀孕和不安全堕胎的风险,以及对产妇健康产生负面影响。尽管已经在埃塞俄比亚研究了 Implanon 停药的规模和决定因素,但结果不一致,存在显著差异。因此,本系统评价和荟萃分析旨在估计埃塞俄比亚 Implanon 停药的总体流行率及其决定因素。
使用 PubMed、Embase、Google Scholar、Scopus、Web of Science、Science Direct 和 Cochrane Library 等电子数据库,对截至 2022 年 2 月 18 日之前发表的研究进行了全面检索。使用 Microsoft Excel 2013 提取相关数据,并使用 STATA 版本 16 进行分析。使用随机效应荟萃分析模型计算合并流行率和比值比。使用 Cochrane 检验统计量和 Q 检验评估纳入研究的异质性。使用漏斗图、贝格检验和埃格检验检查是否存在发表偏倚。
本荟萃分析共纳入 11 项研究,涉及 4320 名研究参与者。发现埃塞俄比亚 Implanon 停药的总体合并流行率为 32.62%(95%置信区间 24.10%,41.13%)。纳入研究之间存在显著异质性( = 97.4%, < 0.001)。然而,没有统计学证据表明存在发表偏倚( = 0.533)。对服务提供不满意(比值比 = 3.92,95%置信区间 1.54,6.29)、无术前咨询(比值比 = 2.98,95%置信区间 1.91,5.04)、无术后随访(比值比 = 4.03,95%置信区间 2.17,5.90)和出现副作用(比值比 = 2.93,95%置信区间 1.87,3.98)被发现是 Implanon 停药的决定因素。
根据这项系统评价和荟萃分析,三分之一的埃塞俄比亚妇女在推荐时间(3 年)之前停止使用 Implanon。项目管理者和服务提供者应考虑采用更多基于证据和参与式的咨询方法,以提高客户满意度。此外,计划生育服务提供点应具备管理和安抚出现副作用的妇女的能力。