Departments of Ophthalmology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan.
J Craniofac Surg. 2022 Sep 1;33(6):e598-e601. doi: 10.1097/SCS.0000000000008681. Epub 2022 Jun 28.
To examine the usefulness and safety of cryotherapy for residual tarsus and free tarsal graft implantation for eyelid reconstruction after excision of malignant eyelid tumor.
Fifteen patients with 17 eyelid malignancies (10 sebaceous gland carcinomas and 7 basal cell carcinomas) who underwent eyelid reconstruction between June 2017 and February 2021 were included in the study. In these patients, the tumors were resected in the entire eyelid layer including the safety margin. Only sebaceous gland carcinomas patients underwent cryotherapy at the residual tarsus margin. Then, a free tarsal graft taken from the ipsilateral or contralateral upper eyelid was transplanted into the eyelid plate defect, and anterior lamella reconstruction was performed with an orbicularis oculi myocutaneous advance flap.
In both the non-cryotherapy and cryotherapy groups, there were no serious complications such as dropout or necrosis of the free tarsal graft. There were no differences in the occurrence of complications such as eyelid retraction or trichiasis between the 2 groups, but 1 patient who underwent cryotherapy required revision surgery to correct eyelid retraction. In addition, there were no complications on the donor side associated with free tarsal graft collection.
The use of a free tarsal graft in the reconstruction of eyelid malignancies is relatively effective and safe, and if vascular support of the anterior lamella is obtained, cryotherapy is less likely to affect the viability of the free tarsal graft and may contribute to a decrease in local recurrence.
探讨冷冻疗法在恶性眼睑肿瘤切除后残余睑板和游离睑板移植重建眼睑中的应用价值和安全性。
纳入 2017 年 6 月至 2021 年 2 月期间 15 例 17 只眼眼睑恶性肿瘤(10 例皮脂腺癌,7 例基底细胞癌)患者,所有患者均行肿瘤全层(包括安全缘)切除。仅皮脂腺癌患者于残余睑板边缘行冷冻治疗。然后,将取自对侧或同侧上睑的游离睑板移植到眼睑板缺损处,并采用眼轮匝肌肌皮瓣行前板重建。
在未行冷冻治疗组和冷冻治疗组中,游离睑板均未出现脱落或坏死等严重并发症。两组患者的并发症(如眼睑退缩或倒睫)发生率无差异,但有 1 例行冷冻治疗的患者需要行修复手术以矫正眼睑退缩。此外,游离睑板采集处未出现与供区相关的并发症。
游离睑板在眼睑恶性肿瘤重建中较为有效且安全,如果能获得前板的血管支持,冷冻治疗不太可能影响游离睑板的活力,并可能有助于降低局部复发率。