新型冠状病毒（COVID-19）疫苗接种后的葡萄膜炎及眼部后部表现
Uveitis and Posterior Ophthalmic Manifestations Following the SARS-CoV-2 (COVID-19) Vaccine.
作者信息
Patel Kishan G, Hilton Taylor, Choi Rene Y, Abbey Ashkan M
机构信息
Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, Missouri, USA.
Texas Retina Associates, Dallas, Texas, USA.
出版信息
Ocul Immunol Inflamm. 2022 Jul;30(5):1142-1148. doi: 10.1080/09273948.2022.2079533. Epub 2022 Jun 28.
PURPOSE
To present four cases of posterior ophthalmic manifestations associated with a temporal relationship to SARS-CoV-2 vaccination.
METHODS
Retrospective case series with a review of clinical findings.
RESULTS
Four patients presented with various posterior ophthalmic findings including uveitis, maculopathy, and optic neuropathy. Each of their clinical courses varied in terms of ophthalmic imaging and exam findings.
CONCLUSION
The coronavirus disease 2019 (COVID-19) pandemic has ushered in a new wave of challenges to healthcare, epidemiological endeavors, and widespread vaccination efforts. Novel vaccines have been developed for the SARS-CoV-2 virus, including both mRNA and viral vector-based platforms. The ocular manifestations and side effects related to the SARS-CoV-2 vaccine is not well established or understood. There may be an association between vaccination and posterior ophthalmic manifestations.
目的
介绍4例与严重急性呼吸综合征冠状病毒2（SARS-CoV-2）疫苗接种存在时间关联的眼部后部表现病例。
方法
回顾性病例系列研究并对临床发现进行回顾。
结果
4例患者出现了包括葡萄膜炎、黄斑病变和视神经病变在内的各种眼部后部表现。他们各自的临床病程在眼科影像学和检查结果方面各不相同。
结论
2019冠状病毒病（COVID-19）大流行给医疗保健、流行病学研究和广泛的疫苗接种工作带来了新一波挑战。已针对SARS-CoV-2病毒研发了新型疫苗，包括基于信使核糖核酸（mRNA）和病毒载体的平台。与SARS-CoV-2疫苗相关的眼部表现和副作用尚未得到充分证实或了解。疫苗接种与眼部后部表现之间可能存在关联。
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