Suppr超能文献

坏疽性脓皮病的发病机制与诊断研究进展

[Research advances on the pathogenesis and diagnosis of pyoderma gangrenosum].

作者信息

Yang L, Yang Q W, Fu Y J

机构信息

The Second Clinical Medical College, Binzhou Medical University, Yantai 264003, China.

The Clinical Medical College, Weifang Medical University, Weifang 261053, China.

出版信息

Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi. 2022 Jun 20;38(6):569-573. doi: 10.3760/cma.j.cn501225-20220331-00117.

Abstract

Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis, closely associated with the immune system. Its pathogenesis is currently not clear. The lack of specificity in the clinical manifestations and histopathological changes of PG leads to a long clinical diagnosis cycle and even misdiagnosis, which is easy to delay treatment or promote the deterioration of ulcer wound. The diagnosis of this disease is still very difficult, which poses a great challenge to wound repair practitioners. This article reviews the research advances on the pathophysiology, clinical features, and diagnosis of PG in recent years, with the aim of providing reference for relevant clinical practitioners.

摘要

坏疽性脓皮病(PG)是一种罕见的嗜中性皮病,与免疫系统密切相关。其发病机制目前尚不清楚。PG临床表现和组织病理学改变缺乏特异性,导致临床诊断周期长,甚至误诊,容易延误治疗或促使溃疡创面恶化。该病的诊断仍然非常困难,这给伤口修复从业者带来了巨大挑战。本文综述了近年来PG在病理生理学、临床特征及诊断方面的研究进展,旨在为相关临床从业者提供参考。

相似文献

1
[Research advances on the pathogenesis and diagnosis of pyoderma gangrenosum].坏疽性脓皮病的发病机制与诊断研究进展
Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi. 2022 Jun 20;38(6):569-573. doi: 10.3760/cma.j.cn501225-20220331-00117.
4
Diagnosis and novel clinical treatment strategies for pyoderma gangrenosum.坏疽性脓皮病的诊断和新型临床治疗策略。
Expert Rev Clin Pharmacol. 2020 Feb;13(2):157-161. doi: 10.1080/17512433.2020.1709825. Epub 2020 Jan 6.
5
Pyoderma gangrenosum.坏疽性脓皮病
Med J Malaysia. 2007 Aug;62(3):251-3.
7
[Pyoderma gangrenosum].[坏疽性脓皮病]
Hautarzt. 2016 Sep;67(9):753-63. doi: 10.1007/s00105-016-3847-6.
8
Tofacitinib in pyoderma gangrenosum - A case series.托法替尼治疗坏疽性脓皮病-病例系列。
Int J Rheum Dis. 2024 Jan;27(1):e14810. doi: 10.1111/1756-185X.14810. Epub 2023 Jul 3.
10
Extracutaneous involvement of pyoderma gangrenosum.坏疽性脓皮病的皮肤外表现。
Arch Dermatol Res. 2019 Aug;311(6):425-434. doi: 10.1007/s00403-019-01912-1. Epub 2019 Mar 29.

本文引用的文献

4
5
Pyoderma gangrenosum.坏疽性脓皮病。
Nat Rev Dis Primers. 2020 Oct 8;6(1):81. doi: 10.1038/s41572-020-0213-x.
6
A Unified Concept of Acne in the PAPA Spectrum Disorders.PAPA 谱系疾病中痤疮的统一概念。
Dermatology. 2021;237(5):827-834. doi: 10.1159/000509874. Epub 2020 Sep 16.
10
Diagnosis and novel clinical treatment strategies for pyoderma gangrenosum.坏疽性脓皮病的诊断和新型临床治疗策略。
Expert Rev Clin Pharmacol. 2020 Feb;13(2):157-161. doi: 10.1080/17512433.2020.1709825. Epub 2020 Jan 6.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验