Suppr超能文献

坏疽性脓皮病的发病机制与诊断研究进展

[Research advances on the pathogenesis and diagnosis of pyoderma gangrenosum].

作者信息

Yang L, Yang Q W, Fu Y J

机构信息

The Second Clinical Medical College, Binzhou Medical University, Yantai 264003, China.

The Clinical Medical College, Weifang Medical University, Weifang 261053, China.

出版信息

Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi. 2022 Jun 20;38(6):569-573. doi: 10.3760/cma.j.cn501225-20220331-00117.

Abstract

Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis, closely associated with the immune system. Its pathogenesis is currently not clear. The lack of specificity in the clinical manifestations and histopathological changes of PG leads to a long clinical diagnosis cycle and even misdiagnosis, which is easy to delay treatment or promote the deterioration of ulcer wound. The diagnosis of this disease is still very difficult, which poses a great challenge to wound repair practitioners. This article reviews the research advances on the pathophysiology, clinical features, and diagnosis of PG in recent years, with the aim of providing reference for relevant clinical practitioners.

摘要

坏疽性脓皮病(PG)是一种罕见的嗜中性皮病,与免疫系统密切相关。其发病机制目前尚不清楚。PG临床表现和组织病理学改变缺乏特异性,导致临床诊断周期长,甚至误诊,容易延误治疗或促使溃疡创面恶化。该病的诊断仍然非常困难,这给伤口修复从业者带来了巨大挑战。本文综述了近年来PG在病理生理学、临床特征及诊断方面的研究进展,旨在为相关临床从业者提供参考。

相似文献

1
[Research advances on the pathogenesis and diagnosis of pyoderma gangrenosum].
Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi. 2022 Jun 20;38(6):569-573. doi: 10.3760/cma.j.cn501225-20220331-00117.
2
[A no scarring persistent skin lesion for 3 years pyoderma gangrenosum].
Pan Afr Med J. 2019 Apr 23;32:198. doi: 10.11604/pamj.2019.32.198.18692. eCollection 2019.
3
[Management of pyoderma gangrenosum. An update on clinical features, diagnosis and therapy].
Hautarzt. 2010 Apr;61(4):345-53; quiz 354-5. doi: 10.1007/s00105-009-1909-8.
4
Diagnosis and novel clinical treatment strategies for pyoderma gangrenosum.
Expert Rev Clin Pharmacol. 2020 Feb;13(2):157-161. doi: 10.1080/17512433.2020.1709825. Epub 2020 Jan 6.
5
Pyoderma gangrenosum.
Med J Malaysia. 2007 Aug;62(3):251-3.
7
[Pyoderma gangrenosum].
Hautarzt. 2016 Sep;67(9):753-63. doi: 10.1007/s00105-016-3847-6.
8
Tofacitinib in pyoderma gangrenosum - A case series.
Int J Rheum Dis. 2024 Jan;27(1):e14810. doi: 10.1111/1756-185X.14810. Epub 2023 Jul 3.
10
Extracutaneous involvement of pyoderma gangrenosum.
Arch Dermatol Res. 2019 Aug;311(6):425-434. doi: 10.1007/s00403-019-01912-1. Epub 2019 Mar 29.

引用本文的文献

1
The Role of Ultra-High-Frequency Ultrasound in Pyoderma Gangrenosum: New Insights in Pathophysiology and Diagnosis.
Diagnostics (Basel). 2023 Aug 30;13(17):2802. doi: 10.3390/diagnostics13172802.
2
[Emphasis on multidisciplinary collaboration in clinical diagnosis and treatment of autoimmune disease-related ulcers].
Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi. 2022 Jun 20;38(6):501-505. doi: 10.3760/cma.j.cn501120-20211112-00385.

本文引用的文献

1
Pyoderma gangrenosum: A systematic review of the molecular characteristics of disease.
Exp Dermatol. 2022 Apr;31(4):498-515. doi: 10.1111/exd.14534. Epub 2022 Feb 15.
2
Case Report: Pyogenic Arthritis, Pyoderma Gangrenosum, and Acne: A Single-Center Experience and Literature Review.
Front Immunol. 2021 Oct 22;12:735851. doi: 10.3389/fimmu.2021.735851. eCollection 2021.
4
Dermatological Manifestations in Inflammatory Bowel Diseases.
J Clin Med. 2021 Jan 19;10(2):364. doi: 10.3390/jcm10020364.
5
Pyoderma gangrenosum.
Nat Rev Dis Primers. 2020 Oct 8;6(1):81. doi: 10.1038/s41572-020-0213-x.
6
A Unified Concept of Acne in the PAPA Spectrum Disorders.
Dermatology. 2021;237(5):827-834. doi: 10.1159/000509874. Epub 2020 Sep 16.
7
The great imitator with no diagnostic test: pyoderma gangrenosum.
Int Wound J. 2020 Dec;17(6):1774-1782. doi: 10.1111/iwj.13466. Epub 2020 Aug 11.
8
Pyoderma gangrenosum associated with limited cutaneous systemic sclerosis: a rare case with literature review.
Clin Rheumatol. 2021 Mar;40(3):1141-1145. doi: 10.1007/s10067-020-05285-z. Epub 2020 Jul 16.
9
Pyoderma gangrenosum: From historical perspectives to emerging investigations.
Int Wound J. 2020 Oct;17(5):1255-1265. doi: 10.1111/iwj.13389. Epub 2020 May 6.
10
Diagnosis and novel clinical treatment strategies for pyoderma gangrenosum.
Expert Rev Clin Pharmacol. 2020 Feb;13(2):157-161. doi: 10.1080/17512433.2020.1709825. Epub 2020 Jan 6.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验