Yang L, Yang Q W, Fu Y J
The Second Clinical Medical College, Binzhou Medical University, Yantai 264003, China.
The Clinical Medical College, Weifang Medical University, Weifang 261053, China.
Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi. 2022 Jun 20;38(6):569-573. doi: 10.3760/cma.j.cn501225-20220331-00117.
Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis, closely associated with the immune system. Its pathogenesis is currently not clear. The lack of specificity in the clinical manifestations and histopathological changes of PG leads to a long clinical diagnosis cycle and even misdiagnosis, which is easy to delay treatment or promote the deterioration of ulcer wound. The diagnosis of this disease is still very difficult, which poses a great challenge to wound repair practitioners. This article reviews the research advances on the pathophysiology, clinical features, and diagnosis of PG in recent years, with the aim of providing reference for relevant clinical practitioners.
坏疽性脓皮病(PG)是一种罕见的嗜中性皮病,与免疫系统密切相关。其发病机制目前尚不清楚。PG临床表现和组织病理学改变缺乏特异性,导致临床诊断周期长,甚至误诊,容易延误治疗或促使溃疡创面恶化。该病的诊断仍然非常困难,这给伤口修复从业者带来了巨大挑战。本文综述了近年来PG在病理生理学、临床特征及诊断方面的研究进展,旨在为相关临床从业者提供参考。