Lebedev V P
Ter Arkh. 1987;59(2):22-5.
A total of 730 young men aged 18 to 22 with peptic ulcer were examined, of them 670 (91.8%) with duodenal ulcer. The follow-up of most patients over time (starting from initial changes up to ulcer formation), a study of risk factors and catamnesis contributed to better understanding of pathogenesis and early diagnosis. Early diagnosis at the stage of acute ulcer (small sizes, weak changes of the gastroduodenal mucosa, high reparative properties and complete cicatrization within a short period) was made in 80% of the patients. In the young men with chronic ulcer (20%) a clinical picture was less typical, a course of disease was torpid, functional indices and reparative properties were on a decrease.
共检查了730名年龄在18至22岁的患有消化性溃疡的青年男性，其中670名（91.8%）患有十二指肠溃疡。对大多数患者进行长期随访（从最初的变化到溃疡形成）、对危险因素和病史的研究有助于更好地理解发病机制和早期诊断。80%的患者在急性溃疡阶段（溃疡面积小、胃十二指肠黏膜变化轻微、修复能力强且短期内完全愈合）得到了早期诊断。在患有慢性溃疡的青年男性（20%）中，临床表现不太典型，病程缓慢，功能指标和修复能力下降。
