Chaima Kouki, Mariem Amouri, Emna Bahloul, Slim Charfi, Fatma Hammemi, Tahya Boudawara, Hamida Turki
Department of Dermatology Hedi Chaker Hospital Sfax Tunisia.
Department of anatomopathology Habib Bourguiba Hospital Sfax Tunisia.
Clin Case Rep. 2022 Jun 19;10(6):e5971. doi: 10.1002/ccr3.5971. eCollection 2022 Jun.
Panniculitis has various etiologies. One of the less common causes is trauma and hence traumatic fat necrosis (FN). These soft tissue injuries usually appear on the shins, thighs, breasts, arms, and buttocks. FN is mainly caused by trauma and may be associated with other conditions such as pancreatic disease. FN arising after intramuscular injections is uncommon and usually appears as firm, encapsulated, mobile, nontender, and solitary or multiple subcutaneous nodules. We report an interesting case of FN caused by intramuscular injections of cefazolin and meglumine antimoniate (MA) in a 38-year-old female patient. MA is regarded as the first-line systemic treatment for cutaneous leishmaniasis (CL). However, these drugs are not devoid of various potentially adverse reactions.
脂膜炎有多种病因。其中较不常见的原因之一是创伤，即创伤性脂肪坏死（FN）。这些软组织损伤通常出现在小腿、大腿、乳房、手臂和臀部。FN主要由创伤引起，可能与其他疾病如胰腺疾病有关。肌肉注射后发生的FN并不常见，通常表现为坚实、有包膜、可移动、无压痛的单个或多个皮下结节。我们报告了一例有趣的FN病例，该病例发生在一名38岁女性患者身上，由肌肉注射头孢唑林和葡甲胺锑酸盐（MA）引起。MA被视为皮肤利什曼病（CL）的一线全身治疗药物。然而，这些药物并非没有各种潜在的不良反应。
