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妊娠晚期肝血管瘤破裂:1例罕见病例报告

Ruptured Hepatic Hemangioma in the Third Trimester of Pregnancy: A Rare Case Report.

作者信息

Ward Haven, Hosseini Omid, Hashimoto Yohey, Soliman Basem

机构信息

School of Medicine, Texas Tech University Health Sciences Center, Lubbock, USA.

School of Medicine, Texas Tech University Health Sciences Center, Amarillo, USA.

出版信息

Cureus. 2022 May 27;14(5):e25397. doi: 10.7759/cureus.25397. eCollection 2022 May.

DOI:10.7759/cureus.25397
PMID:35765393
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9233906/
Abstract

Hepatic hemangiomas are considered the most common benign mesenchymal hepatic tumors. Most cases are asymptomatic. However, giant hemangiomas can present with a variety of clinical presentations, with a rupture being the most catastrophic outcome. Only a few cases of ruptured perinatal hepatic hemangiomas have been reported. Accelerated growth of hepatic hemangiomas caused by increased estrogen in pregnancy, increased intra-abdominal pressure, and direct contact with a gravid uterus are possible mechanisms for increased risk of rupture during pregnancy. The safety of either non-operative or surgical treatment of symptomatic giant hemangioma during pregnancy has not been adequately investigated. We present a rare case of a 28-year-old G1P0 female at 33 weeks gestation that presented with a ruptured hepatic hemangioma treated with damage control surgery followed by nonanatomic surgical resection.

摘要

肝血管瘤被认为是最常见的肝脏间叶性良性肿瘤。大多数病例无症状。然而,巨大血管瘤可表现出多种临床表现,其中破裂是最严重的后果。仅有少数围产期肝血管瘤破裂的病例报道。孕期雌激素增加、腹内压升高以及与妊娠子宫直接接触导致肝血管瘤生长加速,可能是孕期破裂风险增加的机制。孕期有症状的巨大血管瘤非手术或手术治疗的安全性尚未得到充分研究。我们报告一例罕见病例,一名28岁、孕1产0、妊娠33周的女性,因肝血管瘤破裂接受了损伤控制手术,随后进行了非解剖性手术切除。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/85da/9233906/feb7c0803c2d/cureus-0014-00000025397-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/85da/9233906/016721ee50de/cureus-0014-00000025397-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/85da/9233906/687df18a7691/cureus-0014-00000025397-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/85da/9233906/feb7c0803c2d/cureus-0014-00000025397-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/85da/9233906/016721ee50de/cureus-0014-00000025397-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/85da/9233906/687df18a7691/cureus-0014-00000025397-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/85da/9233906/feb7c0803c2d/cureus-0014-00000025397-i03.jpg

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本文引用的文献

1
Successful Management of Intraoperatively Diagnosed Ruptured Spontaneous Sub-Capsular Liver Hematoma in a Woman with Preeclampsia.成功治疗一名子痫前期女性患者术中诊断出的自发性肝包膜下血肿破裂
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肝血管瘤自发性破裂:文献综述
World J Hepatol. 2010 Dec 27;2(12):428-33. doi: 10.4254/wjh.v2.i12.428.
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Clin Exp Pharmacol Physiol. 1996 Mar;23(3):247-50. doi: 10.1111/j.1440-1681.1996.tb02605.x.