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单中心比较第一代与第二代可植入式心脏监测器在儿科患者中的应用经验

A Single-center Experience Comparing First- Versus Second-generation Insertable Cardiac Monitors in Pediatric Patients.

作者信息

Miller Nathan, Roelle Lisa, Lorimer Dean, Dalal Aarti S, Orr William B, Van Hare George F, Avari Silva Jennifer N

机构信息

Electrophysiology Laboratory, St. Louis Children's Hospital, St. Louis, MO, USA.

Division of Pediatric Cardiology, Department of Pediatrics, Washington University School of Medicine, St. Louis, MO, USA.

出版信息

J Innov Card Rhythm Manag. 2022 Jun 15;13(6):5048-5056. doi: 10.19102/icrm.2022.130605. eCollection 2022 Jun.

Abstract

Insertable cardiac monitors (ICMs) have undergone advancements in size and functionality over the past decade, resulting in the introduction of small, easily insertable devices capable of long-term remote monitoring. We define first-generation ICMs as implantable cardiac monitoring devices that require an incision and surgical creation of a subcutaneous pocket and second-generation ICMs as devices implanted using a custom-made tool for subcutaneous insertion, respectively. The aim of this study was to understand the differences between first- and second-generation pediatric ICM implants, implant indications, and time to diagnosis. We performed a retrospective, single-center chart review of patients who underwent ICM implantation from 2009-2019, spanning a 5-year course of first-generation ICM implantations and 5-year course of second-generation ICM implantations. Demographic data, past medical history, implant indication, and time to diagnosis were obtained. A total of 208 patients were identified over the 10-year time period, including 38 (18%) who underwent implantation with a first-generation device and 170 (82%) who underwent implantation with a second-generation device. Implant indications for first-generation ICMs included syncope (71%), palpitations (16%), inherited arrhythmia syndrome (IAS) management (5%), and premature ventricular contractions/ventricular tachycardia (VT) (8%); implant indications for second-generation ICMs included syncope (48%), palpitations (19%), IAS management (40%), premature ventricular contractions/VT (11%), atrial fibrillation (2%), tachycardia (3%), and heart block (0.5%). The average time to diagnosis was 38 weeks for patients with first-generation devices and 55 weeks for those with second-generation devices. With innovations in ICM technologies, there are expanding indications for ICM implantation in pediatric patients for long-term monitoring, specifically regarding the management of IAS patients.

摘要

在过去十年中,可插入式心脏监测器(ICM)在尺寸和功能方面取得了进展,从而推出了体积小、易于插入且能够进行长期远程监测的设备。我们将第一代ICM定义为需要切开并通过手术创建皮下囊袋的植入式心脏监测设备,将第二代ICM定义为分别使用定制工具进行皮下插入的植入设备。本研究的目的是了解第一代和第二代儿科ICM植入、植入适应症以及诊断时间之间的差异。我们对2009年至2019年接受ICM植入的患者进行了回顾性单中心病历审查,涵盖了5年的第一代ICM植入过程和5年的第二代ICM植入过程。获取了人口统计学数据、既往病史、植入适应症和诊断时间。在这10年期间共识别出208例患者,其中38例(18%)接受了第一代设备植入,170例(82%)接受了第二代设备植入。第一代ICM的植入适应症包括晕厥(71%)、心悸(16%)、遗传性心律失常综合征(IAS)管理(5%)以及室性早搏/室性心动过速(VT)(8%);第二代ICM的植入适应症包括晕厥(48%)、心悸(19%)、IAS管理(40%)、室性早搏/VT(11%)、心房颤动(2%)、心动过速(3%)和心脏传导阻滞(0.5%)。第一代设备患者的平均诊断时间为38周,第二代设备患者为5周。随着ICM技术的创新,儿科患者ICM植入用于长期监测(特别是关于IAS患者的管理)的适应症正在不断扩大。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2093/9221184/8551684928a3/icrm-13-5048-g001.jpg

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