Psychosocial Department, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, China.
J Nerv Ment Dis. 2022 Jul 1;210(7):541-546. doi: 10.1097/NMD.0000000000001478. Epub 2022 Jan 12.
Psychiatric disorders (depression/anxiety) and sleep quality are linked to coronary artery disease (CAD). CAD patients often complain of various physical symptoms (PSs), which are not only organic changes of biological origin, but also somatization of mental illness. PSs also affect CAD progression. However, the relationship between psychiatric disorders/sleep quality and PS in CAD is less studied, which this study aims to clarify. This cross-sectional observational study was conducted on the first 305 CAD patients diagnosed with PS by Patient Health Questionnaire-15. They were compared with 521 other CAD patients showing no PS. On multivariate analysis, sex, age, family history, psychiatric disorders, and sleep quality were the significant independent predictors of PS. A significant correlation was found between PS severity and the severity of both psychiatric disorders and sleep quality. Further studies are warranted to explore the impact of psychological and sleep intervention on PS and long-term outcomes.
精神障碍（抑郁/焦虑）和睡眠质量与冠状动脉疾病（CAD）有关。CAD 患者常抱怨各种躯体症状（PSs），这些 PSs 不仅是生物源性的器质性变化，也是精神疾病的躯体化。PSs 也会影响 CAD 的进展。然而，精神障碍/睡眠质量与 CAD 中的 PS 之间的关系研究较少，本研究旨在阐明这一关系。本横断面观察性研究纳入了 305 名经患者健康问卷-15 诊断为 PS 的 CAD 患者，并与 521 名无 PS 的其他 CAD 患者进行了比较。多变量分析显示，性别、年龄、家族史、精神障碍和睡眠质量是 PS 的显著独立预测因素。PS 的严重程度与精神障碍和睡眠质量的严重程度之间存在显著相关性。需要进一步的研究来探讨心理和睡眠干预对 PS 和长期结局的影响。
