Crim Julia, Layfield Lester J
University of Missouri at Columbia, Columbia, MO, USA.
Skeletal Radiol. 2023 Mar;52(3):379-392. doi: 10.1007/s00256-022-04099-1. Epub 2022 Jun 29.
This review examines findings of musculoskeletal neoplasms whose equivocal imaging and/or histopathologic features make it difficult to determine if they will show aggressive behavior. We include both intermediate tumors as defined by the World Health Organization (WHO), and a single low-grade malignancy, low-grade central osteosarcoma, which mimics a benign lesion on imaging and histology. Intermediate tumors are a broad category and are subdivided into tumors that have risk of local recurrence only, and ones that have a risk of distant limb and pulmonary metastases. Difficult intermediate musculoskeletal lesions include atypical cartilaginous tumor/grade 1 chondrosarcoma, atypical lipomatous tumor/grade 1 liposarcoma, and solitary fibrous tumor. We review diagnostic criteria, differential diagnosis, and recommendations for surveillance.
本综述探讨了肌肉骨骼肿瘤的相关研究结果，这些肿瘤的影像学表现和/或组织病理学特征不明确，难以判断它们是否会表现出侵袭性。我们纳入了世界卫生组织（WHO）定义的中间型肿瘤，以及一种低级别恶性肿瘤——低级别中央型骨肉瘤，其在影像学和组织学上类似良性病变。中间型肿瘤是一个广泛的类别，可细分为仅具有局部复发风险的肿瘤，以及具有远处肢体和肺转移风险的肿瘤。难以诊断的中间型肌肉骨骼病变包括非典型软骨肿瘤/1级软骨肉瘤、非典型脂肪瘤性肿瘤/1级脂肪肉瘤和孤立性纤维性肿瘤。我们回顾了诊断标准、鉴别诊断以及监测建议。
