Chair of Epidemiology, University Augsburg, University Hospital Augsburg, Augsburg, Germany.
Institute for Medical Information Processing, Biometry and Epidemiology-IBE, Ludwig-Maximilians-Universität München, Munich, Germany.
PLoS One. 2022 Jun 29;17(6):e0266318. doi: 10.1371/journal.pone.0266318. eCollection 2022.
Much is known about the association between physical activity and the occurrence of stroke. However, the evidence about the correlation between pre-stroke physical activity and post-stroke quality of life remains inconsistent. Thus, there is a high public health relevance to the topic.
The aim of this study was to investigate the association between pre-stroke physical activity and physical quality of life after three months.
Data arises from 858 patients with stroke included a prospective single-centre observational cohort study in Augsburg, Germany, between September 2018 and November 2019. The participants were recruited at the Department of Neurology and Clinical Neurophysiology, University Hospital of Augsburg after their stroke event. The level of physical activity was determined following the short form of the International Physical Activity Questionnaire at baseline. Physical quality of life was assessed three months after hospital discharge using the German version of the Stroke Impact Scale (SIS). A multiple linear regression model and a quantile regression were carried out.
A total of 497 patients were included in the analysis (mean age 69.6, 58.8% male), 26.2% had a high, 18.9% a moderate and 54.9% a low level of pre-stroke physical activity. Patients with high pre-stroke physical activity had a significantly better physical quality of life three months after stroke in the SIS physical domain (beta = 4.1) and in the SIS subdomains hand function (beta = 5.6), mobility (beta = 4.1) and activities of daily living (beta = 3.7). In the physical domain and the subdomain mobility, the effect was especially strong for persons with low physical quality of life after three months.
Pre-stroke physical activity seems to have an important and positive association with physical quality of life after three months in patients with mild disability. Further studies are needed to confirm these results.
人们对体力活动与中风发生之间的关系有了很多了解。然而，关于中风前体力活动与中风后生活质量之间的相关性的证据仍然不一致。因此，这个话题与公众健康密切相关。
本研究旨在调查中风前体力活动与中风后三个月身体生活质量之间的关系。
数据来自德国奥格斯堡的一项前瞻性单中心观察队列研究，该研究于 2018 年 9 月至 2019 年 11 月期间进行。参与者是在奥格斯堡大学医院神经内科和临床神经生理学系中风后招募的。在基线时，使用国际体力活动问卷短表确定体力活动水平。在出院后三个月使用德国版中风影响量表（SIS）评估身体生活质量。进行了多元线性回归模型和分位数回归分析。
共有 497 名患者纳入分析（平均年龄 69.6 岁，58.8%为男性），26.2%的患者体力活动水平较高，18.9%的患者体力活动水平中等，54.9%的患者体力活动水平较低。在中风后三个月，体力活动水平较高的患者在 SIS 身体领域（beta=4.1）和 SIS 子领域手功能（beta=5.6）、移动能力（beta=4.1）和日常生活活动（beta=3.7）方面的身体生活质量明显更好。在身体领域和移动能力子领域，对于三个月后身体生活质量较低的患者，这种影响尤为强烈。
中风前的体力活动似乎与轻度残疾患者中风后三个月的身体生活质量有重要的积极关联。需要进一步的研究来证实这些结果。
