Department of Oral and Maxillofacial Radiology, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8553, Japan.
Department of Oral and Maxillofacial Radiology, Hiroshima University Hospital, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8553, Japan.
Sci Rep. 2022 Jun 29;12(1):10993. doi: 10.1038/s41598-022-15184-9.
T2 mapping allows quantification of the temporomandibular joint (TMJ) ultrastructural degeneration. The study aimed to assess intra- and inter-examination reproducibility of T2 mapping for TMJ evaluation at 3.0 Tesla (T). Seventeen volunteers, regardless of temporomandibular disorder (TMD) diagnosis, received magnetic resonance (MR) examination at 3.0 T. T2 mapping was performed twice (> 5 min between sessions without repositioning) on 12 volunteers to ensure intra-examination reproducibility. Nine volunteers underwent two examinations (> 6 months) to ensure inter-examination reproducibility. The regions of interest (ROIs) of the articular disc and retrodiscal tissue were manually selected and calculated. The mean T2 values of the articular disc and retrodiscal tissue were 25.3 ± 3.0 and 30.0 ± 4.1 ms, respectively. T2 mapping showed excellent intra-examination intraclass correlation coefficients (ICCs) for both articular disc (0.923) and retrodiscal tissue (0.951). Very strong correlations (r) were observed in both articular disc (0.928) and retrodiscal tissue (0.953) (P < .001). Inter-examination reproducibility also demonstrated that the ICCs were excellent (0.918, 0.935) on both ROIs. T2 values between first and second examinations were strongly correlated (r = 0.921, 0.939) (P < .001). In conclusion, T2 mapping seems to be a promising tool for TMJ assessment, regardless of the TMJ condition.
T2 映射可定量评估颞下颌关节 (TMJ) 的超微结构退变。本研究旨在评估 3.0T 下 T2 映射评估 TMJ 的内部和外部检查可重复性。17 名志愿者，无论是否患有颞下颌关节紊乱 (TMD)，均在 3.0T 下接受磁共振 (MR) 检查。12 名志愿者进行了两次 T2 映射（两次检查之间至少间隔 5 分钟，无需重新定位）以确保内部检查的可重复性。9 名志愿者接受了两次检查（两次检查之间间隔超过 6 个月）以确保外部检查的可重复性。手动选择并计算关节盘和关节盘后组织的感兴趣区 (ROI)。关节盘和关节盘后组织的平均 T2 值分别为 25.3±3.0 和 30.0±4.1ms。T2 映射显示关节盘和关节盘后组织的内部检查组内相关系数 (ICC) 均非常好（0.923 和 0.951）。在关节盘（0.928）和关节盘后组织（0.953）中均观察到非常强的相关性（r）（P<.001）。外部检查重复性也表明两个 ROI 的 ICC 均非常好（0.918，0.935）。第一次和第二次检查之间的 T2 值呈强相关（r=0.921，0.939）（P<.001）。总之，无论 TMJ 状况如何，T2 映射似乎都是评估 TMJ 的一种很有前途的工具。
