高度疑似副肿瘤性天疱疮病例中的心肌损伤：一例报告及文献综述
Myocardial Damage in a Highly Suspected Case With Paraneoplastic Pemphigus: A Case Report and Literature Review.
作者信息
Du Xiao, Zhang Miao, Zhang Shilan, Tian Feng, Wen Tie, Liu Ling
机构信息
Department of Cardiovascular Medicine, The Second Xiangya Hospital, Central South University, Changsha, China.
Research Institute of Blood Lipid and Atherosclerosis, Central South University, Changsha, China.
出版信息
Front Med (Lausanne). 2022 Jun 13;9:917050. doi: 10.3389/fmed.2022.917050. eCollection 2022.
Paraneoplastic pemphigus (PNP) is a rare mucocutaneous autoimmune disease. It has multiple clinical accompanied symptoms by affecting various types of epithelia, including the gastrointestinal and respiratory tract. However, an extensive review of the literature found no cases of PNP associated with myocardial damage. Here, we present a 56-year-old male patient with clinically and histopathologically typical paraneoplastic pemphigus (PNP), who had sustained myocardial injury due to non-cardiac disease involvement. Therefore, we suppose that, when persistent cardiac necrosis markers are elevated in patients with paraneoplastic pemphigus (PNP), the possibility of concomitant myocardial damage should get more attention from clinicians to obtain quick diagnosis and treatment.
副肿瘤性天疱疮（PNP）是一种罕见的黏膜皮肤自身免疫性疾病。它通过影响包括胃肠道和呼吸道在内的各种上皮细胞而出现多种临床伴随症状。然而，广泛的文献综述未发现有副肿瘤性天疱疮与心肌损伤相关的病例。在此，我们报告一名56岁男性患者，其具有临床和组织病理学典型的副肿瘤性天疱疮（PNP），因非心脏疾病累及而出现持续性心肌损伤。因此，我们推测，当副肿瘤性天疱疮（PNP）患者的心脏坏死标志物持续升高时，临床医生应更关注其合并心肌损伤的可能性，以便快速诊断和治疗。
Zotero 插件